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Liquisolid technique for dissolution rate enhancement of a high dose water-insoluble drug (carbamazepine).
Different liquisolid formulations of carbamazepine were accomplished by dissolving the drug in the non-toxic hydrophilic liquids, and adsorbing the solution onto the surface of silica. In order toExpand
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The microsponge delivery system of benzoyl peroxide: preparation, characterization and release studies.
Benzoyl peroxide (BPO) is commonly used in topical formulations for the treatment of acne and athletes foot. Skin irritation is a common side effect, and it has been shown that controlled release ofExpand
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The influence of physical properties and morphology of crystallised lactose on delivery of salbutamol sulphate from dry powder inhalers.
The aim of this work was to investigate the mechanistic evaluation of physicochemical properties of new engineered lactose on aerosolisation performance of salbutamol sulphate (SS) delivered from dryExpand
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Kinetic analysis of drug release from nanoparticles.
PURPOSE Comparative drug release kinetics from nanoparticles was carried out using conventional and our novel models with the aim of finding a general model applicable to multi mechanistic release.Expand
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The effect of penetration enhancers on drug delivery through skin: a QSAR study.
Skin penetration enhancers are used to allow formulation of transdermal delivery systems for drugs that are otherwise insufficiently skin-permeable. A full understanding of the mode of action couldExpand
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Enhancement of dissolution rate of piroxicam using liquisolid compacts.
Piroxicam is a poorly soluble, highly permeable drug and the rate of its oral absorption is often controlled by the dissolution rate in the gastrointestinal. The poor dissolution rate ofExpand
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Influence of lactose carrier particle size on the aerosol performance of budesonide from a dry powder inhaler
The purpose of this study was to evaluate the effect of carrier particle size on properties of dry powder and its effect on dry powder inhaler (DPI) performance. Commercial α-lactose-monohydrate, aExpand
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Liquisolid technique as a new approach to sustain propranolol hydrochloride release from tablet matrices.
It is suggested here that liquisolid technique has the potential to be optimized for the reduction of drug dissolution rate and thereby production of sustained release systems. In the present study,Expand
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Dry powder inhalers: mechanistic evaluation of lactose formulations containing salbutamol sulphate.
The purpose of this study was to evaluate the relationships between physicochemical properties and aerosolisation performance of different grades of lactose. In order to get a wide range ofExpand
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An Investigation of Physicochemical Properties of Piroxicam Liquisolid Compacts
The potential of liquisolid systems to improve the dissolution properties of a water-insoluble agent (piroxicam) was investigated. In this study, physicochemical properties of piroxicam liquisolidExpand
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