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SLC47A1 wt Allele

Known as: MATE1, MATE-1, hMATE-1 
Human SLC47A1 wild-type allele is located in the vicinity of 17p11.2 and is approximately 84 kb in length. This allele, which encodes multidrug and… 
National Institutes of Health

Related topics

Related topics

7 relations
Homo sapiensIonophore activityLigand BindingMolecular Transport

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Endotoxin Modulates the Expression of Renal Drug Transporters in HIV-1 Transgenic Rats.
PURPUSE Bacterial co-infections and low grade endotoxemia are common in HIV patients. Inflammation due to endotoxin or HIV may… 
2018
2018
Indinavir Alters the Pharmacokinetics of Lamivudine Partially via Inhibition of Multidrug and Toxin Extrusion Protein 1 (MATE1)
Lamivudine, a characterized substrate for human multidrug and toxin extrusion protein 1 (hMATE1) in vitro, was commonly used with… 
2017
2017
MATE-1 modulation by kinin B1 receptor enhances cisplatin efflux from renal cells
Cisplatin is a drug widely used in chemotherapy that frequently causes severe renal dysfunction. Organic transporters have an… 
2017
2017
MATE-1 modulation by kinin B1 receptor enhances cisplatin efflux from renal cells
Cisplatin is a drug widely used in chemotherapy that frequently causes severe renal dysfunction. Organic transporters have an… 
2016
2016
The MATE1 rs2289669 polymorphism affects the renal clearance of metformin following ranitidine treatment.
PURPOSE Human multidrug and toxin extrusion member 1 (MATE1, SLC47A1) and Organic Cation Transporter 2 (OCT2, SLC22A2) play… 
2015
2015
[Establishment of MDCK cell models expressing human MATE1 or co-expressing with human OCT1 or OCT2].
To establish single- and double-transfected transgenic cells stably expressing hMATE1, hMATE1 cDNA was cloned by RT-PCR from… 
2013
2013
Ischemia/Reperfusion-inducible protein modulates the function of organic cation transporter 1 and multidrug and toxin extrusion 1.
The recently identified ischemia/reperfusion-inducible protein (IRIP) has been reported to negatively modulate the activities of… 
2013
2013
Identification and functional characterization of novel MATE1 genetic variations in Koreans.
2012
2012
Abstract LB-345: Differences in metformin transporter expression between breast tumor and breast cancer cell lines: selecting a relevant breast cancer cell model for metformin therapy
Proceedings: AACR 103rd Annual Meeting 2012‐‐ Mar 31‐Apr 4, 2012; Chicago, IL Purpose: Recent studies show that the anti… 
Highly Cited
2010
Highly Cited
2010
Heterozygous variants of multidrug and toxin extrusions (MATE1 and MATE2-K) have little influence on the disposition of metformin in diabetic patients.
Multidrug and toxin extrusions (MATE1/SLC47A1 and MATE2-K/SLC47A2) play important roles in the renal excretion of metformin. We… 
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