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SLC3A2 wt Allele

Known as: CD98, 4F2, Solute Carrier Family 3 (Activators of Dibasic And Neutral Amino Acid Transport), Member 2 Gene 
Human SLC3A2 wild-type allele is located in the vicinity of 11q13 and is approximately 33 kb in length. This allele, which encodes 4F2 cell-surface… 
National Institutes of Health

Related topics

Related topics

6 relations
11q13Homo sapiensIonophore activityLigand Binding

Papers overview

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Highly Cited
2012
Highly Cited
2012
Relation of LAT1/4F2hc expression with pathological grade, proliferation and angiogenesis in human gliomas
BackgroundLAT1/4F2hc heterodimeric complex is a major route for the transport of large neutral essential amino acids through the… 
Review
2010
Review
2010
Cancer-related issues of CD147.
CD147 is involved in many physiological functions, such as lymphocyte responsiveness, spermatogenesis, implantation… 
Highly Cited
2008
Highly Cited
2008
Enhanced tumor growth elicited by L-type amino acid transporter 1 in human malignant glioma cells.
OBJECTIVE To study the expression and function of L-type amino acid transporter 1 (LAT1), a major catalytic subunit of system L… 
Highly Cited
2005
Highly Cited
2005
CD98hc (SLC3A2) mediates integrin signaling.
Integrins regulate cellular behaviors through signaling pathways, including Rho GTPases and kinases. CD98 heterodimers, comprised… 
Highly Cited
2002
Highly Cited
2002
Distribution of Cystine/Glutamate Exchange Transporter, System xc−, in the Mouse Brain
Mammalian cells express a transport system known as system xc−, which is an exchange agency specific for anionic forms of cystine… 
Highly Cited
2000
Highly Cited
2000
Identification and Characterization of a Na+-independent Neutral Amino Acid Transporter That Associates with the 4F2 Heavy Chain and Exhibits Substrate Selectivity for Small Neutral d- and l-Amino…
A cDNA was isolated from the mouse brain that encodes a novel Na+-independent neutral amino acid transporter. The encoded protein… 
Review
2000
Review
2000
Surface Antigen CD98(4F2): Not a Single Membrane Protein, But a Family of Proteins with Multiple Functions
CD98(4F2) belongs to a group of approximately two hundred proteins at the surface of leukocytes that are thought to be important… 
Highly Cited
1998
Highly Cited
1998
Amino-acid transport by heterodimers of 4F2hc/CD98 and members of a permease family
Amino-acid transport across cellular plasma membranes depends on several parallel-functioning (co-)transporters and exchangers… 
Highly Cited
1992
Highly Cited
1992
The 4F2 antigen heavy chain induces uptake of neutral and dibasic amino acids in Xenopus oocytes.
Highly Cited
1982
Highly Cited
1982
Characterization of antigen recognized by the monoclonal antibody (4F2): different molecular forms on human T and B lymphoblastoid cell lines.
The monoclonal antibody 4F2 recognizes a disulfide-linked ricin-binding glycoprotein complex (Mr congruent to 125,000) composed… 
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