SLC22A8 gene

Known as: SOLUTE CARRIER FAMILY 22 (ORGANIC ANION TRANSPORTER), MEMBER 8, OAT3, ORGANIC ANION TRANSPORTER 3 
 
National Institutes of Health

Papers overview

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2013
2013
Veliparib (ABT-888) is largely eliminated as parent drug in human urine (70% of the dose). Renal unbound clearance exceeds… (More)
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Highly Cited
2007
Highly Cited
2007
This study was designed to quantitatively assess the mRNA expression of 36 important drug transporters in human jejunum, colon… (More)
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2007
2007
Ischemic acute renal failure (iARF) was described to reduce renal extraction of the organic anion para-aminohippurate (PAH) in… (More)
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2006
2006
The human organic anion transporter, OAT3 (SLC22A8), plays a critical role in renal drug elimination, by mediating the entry of a… (More)
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2005
2005
Tryptophan metabolites such as kynurenate (KYNA), xanthurenate (XA), and quinolinate are considered to have an important impact… (More)
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Highly Cited
2004
Highly Cited
2004
The function of hepatic transporters is to move organic substances across sinusoidal and canalicular membranes. During… (More)
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Highly Cited
2003
Highly Cited
2003
OBJECTIVE Our objective was to quantitate the contribution of the genetic polymorphisms of the genes for 2 human organic anion… (More)
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Highly Cited
2003
Highly Cited
2003
Basolateral uptake of organic anions in renal proximal tubule cells is indirectly coupled to the Na(+) gradient through Na… (More)
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Highly Cited
2002
Highly Cited
2002
To begin to develop in vivo model systems for the assessment of the contributions of specific organic anion transporter (OAT… (More)
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Highly Cited
2002
Highly Cited
2002
Our previous kinetic analyses have shown that the transporter responsible for the renal uptake of pravastatin, an HMG-CoA… (More)
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