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SLC22A2 wt Allele

Known as: HOCT2, OCT2, Solute Carrier Family 22 (Organic Cation Transporter), Member 2 wt Allele 
Human SLC22A2 wild-type allele is located in the vicinity of 6q25.3 and is approximately 107 kb in length. This allele, which encodes solute carrier… Expand
National Institutes of Health

Papers overview

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2014
2014
Rhodamine 123 is a fluorescent cationic dye commonly used as a mitochondrial probe and known or suspected to be transported by… Expand
Highly Cited
2013
Highly Cited
2013
Recently the clinical importance of human organic cation transporters 1 (hOCT1/SLC22A1) and 2 (hOCT2/SLC22A2) in drug disposition… Expand
Highly Cited
2012
Highly Cited
2012
Cimetidine, an H2 receptor antagonist, has been used to investigate the tubular secretion of organic cations in human kidney. We… Expand
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2012
2012
Besides the three antidepressant-sensitive, Na+- and Cl−-dependent monoamine transporters, Na+-independent organic cation… Expand
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Highly Cited
2011
Highly Cited
2011
Agmatine is a biogenic amine (l-arginine metabolite) of potential relevance to several central nervous system (CNS) conditions… Expand
2009
2009
Although some guanidine compounds were reported as superior substrates for organic cation transporter (OCT)2 than OCT1, it was… Expand
Highly Cited
2006
Highly Cited
2006
Polyspecific organic cation transporters (OCTs) have a large substrate binding pocket with different interaction domains. To… Expand
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Highly Cited
2005
Highly Cited
2005
Human organic cation transporters (hOCTs) are expressed in organs of drug absorption and elimination and play an important role… Expand
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Highly Cited
2002
Highly Cited
2002
The purpose of this study was to elucidate the interactions of human organic anion transporters (hOATs) and human organic cation… Expand
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2000
2000
In the kidney, a number of transport proteins involved in the secretion of permanently charged organic cations have recently been… Expand