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SLC22A2 gene

Known as: OCT2, Solute Carrier Family 22 (Organic Cation Transporter), Member 2 Gene, SOLUTE CARRIER FAMILY 22 (ORGANIC CATION TRANSPORTER), MEMBER 2 
This gene is involved in mediating the uptake of organic compounds.
National Institutes of Health

Papers overview

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Highly Cited
2013
Highly Cited
2013
Polyamines are ubiquitous organic cations implicated in many physiological processes. Because they are positively charged at… Expand
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Highly Cited
2012
Highly Cited
2012
BackgroundSusceptibility to cisplatin (CDDP) nephrotoxicity is known to vary between individuals, but the basis of this variation… Expand
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Highly Cited
2011
Highly Cited
2011
Metformin, an oral insulin-sensitizing drug, is actively transported into cells by organic cation transporters (OCT) 1, 2, and 3… Expand
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Highly Cited
2010
Highly Cited
2010
Renal elimination of a number of cationic compounds is thought to be mediated by the organic cation transporter 2 (OCT2, SLC22A2… Expand
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Highly Cited
2008
Highly Cited
2008
The organic cation transporter 2 (OCT2) provides an important pathway for the uptake of cationic compounds in the kidney, which… Expand
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Highly Cited
2008
Highly Cited
2008
Genetic variants of the organic cation transporter 2 (protein, OCT2; gene, SLC22A2) were evaluated for their contribution to the… Expand
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Highly Cited
2008
Highly Cited
2008
We have identified unique chemical and biological properties of a cationic monofunctional platinum(II) complex, cis-diammine… Expand
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Highly Cited
2005
Highly Cited
2005
Human organic cation transporters (hOCTs) are expressed in organs of drug absorption and elimination and play an important role… Expand
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Highly Cited
2001
Highly Cited
2001
Imprinting of the maternally-expressed Igf2r gene is controlled by an intronic imprint control element (ICE) known as Region2… Expand
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Highly Cited
1997
Highly Cited
1997
Polyspecific transporters for organic cations (OCT) belong to a new protein family which also include organic anion transporters… Expand
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