SLC22A2 gene

Known as: OCT2, Solute Carrier Family 22 (Organic Cation Transporter), Member 2 Gene, SOLUTE CARRIER FAMILY 22 (ORGANIC CATION TRANSPORTER), MEMBER 2 
This gene is involved in mediating the uptake of organic compounds.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1997-2017
0102019972017

Papers overview

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2013
2013
Polyamines are ubiquitous organic cations implicated in many physiological processes. Because they are positively charged at… (More)
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2012
2012
Susceptibility to cisplatin (CDDP) nephrotoxicity is known to vary between individuals, but the basis of this variation has not… (More)
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Highly Cited
2010
Highly Cited
2010
Renal elimination of a number of cationic compounds is thought to be mediated by the organic cation transporter 2 (OCT2, SLC22A2… (More)
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2008
2008
The organic cation transporter 2 (OCT2) provides an important pathway for the uptake of cationic compounds in the kidney, which… (More)
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Highly Cited
2008
Highly Cited
2008
Genetic variants of the organic cation transporter 2 (protein, OCT2; gene, SLC22A2) were evaluated for their contribution to the… (More)
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2007
2007
An important function of hepatocytes is the biliary elimination of endogenous and xenobiotic small molecules, many of which are… (More)
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Highly Cited
2006
Highly Cited
2006
The nephrotoxicity of the nucleotide antivirals adefovir, cidofovir and tenofovir is considered to depend on the renal tubular… (More)
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2005
2005
OCT1 and OCT2 are involved in renal secretion of cationic drugs. Although they have similar selectivity for some substrates (e.g… (More)
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Highly Cited
2001
Highly Cited
2001
Imprinting of the maternally-expressed Igf2r gene is controlled by an intronic imprint control element (ICE) known as Region2… (More)
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1997
1997
Polyspecific transporters for organic cations (OCT) belong to a new protein family which also include organic anion transporters… (More)
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