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SLC22A2 gene

Known as: OCT2, Solute Carrier Family 22 (Organic Cation Transporter), Member 2 Gene, SOLUTE CARRIER FAMILY 22 (ORGANIC CATION TRANSPORTER), MEMBER 2 
This gene is involved in mediating the uptake of organic compounds.
National Institutes of Health

Related topics

Related topics

9 relations
Homo sapiensIonophore activityLigand BindingMolecular Transport

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Organic Cation Transporter 2 (OCT2/SLC22A2) Gene Variation in the South African Bantu-Speaking Population and Functional Promoter Variants.
SLC22A2 facilitates the transport of endogenous and exogenous cationic compounds. Many pharmacologically significant compounds… 
2015
2015
The variant organic cation transporter 2 (OCT2)-T201M contribute to changes in insulin resistance in patients with type 2 diabetes treated with metformin.
Review
2015
Review
2015
No relationship between drug transporter genetic variants and tenofovir plasma concentrations or changes in glomerular filtration rate in HIV-infected adults.
Host genetics of drug transporters located in the renal tubule may contribute towards tenofovir disoproxil fumarate (TDF… 
2015
2015
Genomewide association study of tenofovir pharmacokinetics and creatinine clearance in AIDS Clinical Trials Group protocol A5202
Background Tenofovir disoproxil fumarate (TDF) causes kidney toxicity in some patients. We carried out genomewide analyses to… 
2013
2013
Regulation of cell proliferation by the guanosine–adenosine mechanism: role of adenosine receptors
A recent study (American Journal of Physiology – Cell Physiology 304:C406–C421, 2013) suggests that extracellular guanosine… 
2012
2012
Cellular Pharmacokinetic/Pharmacodynamic Relationship of Platinum Cytostatics in Head and Neck Squamous Cell Carcinoma Evaluated by Liquid Chromatography Coupled to Tandem Mass Spectrometry
Cisplatin (diaminodichloroplatinum) is the favored platinum (Pt) drug for the treatment of head and neck squamous cell carcinoma… 
2011
2011
Screening of genetic variations of SLC15A2, SLC22A1, SLC22A2 and SLC22A6 genes
A growing list of membrane-spanning proteins involved in the transport of a large variety of drugs has been recognized and… 
Review
2009
Review
2009
Organic cation transporters: physiology, toxicology and special focus on ethidium as a novel substrate.
The polyspecific organic cation transporters OCT1 (SLC22A1), OCT2 (SLC22A2) and OCT3 (SLC22A3) mediate facilitated and… 
2004
2004
Pharmacogenetic meta‐analysis suggests that atrasentan is an organic anion transport protein C substrate
Review
2003
Review
2003
PharmGKB Update: I. Genetic Variants of the Organic Cation Transporter 2 (OCT2, SLC22A2)
Category: genotype PharmGKB Submission Number: PS202784 Project: Pharmacogenetics of Membrane Transporters HGNC Symbol… 
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