SLC1A1 gene

Known as: EAAC1, solute carrier family 1 member 1, SOLUTE CARRIER FAMILY 1 (NEURONAL/EPITHELIAL HIGH AFFINITY GLUTAMATE TRANSPORTER), MEMBER 1 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1984-2017
0102019842017

Papers overview

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Highly Cited
2006
Highly Cited
2006
CONTEXT There is strong evidence from family and twin studies that genetic determinants play an important role in the etiology of… (More)
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Highly Cited
2006
Highly Cited
2006
CONTEXT The first 2 independent linkage studies for obsessive-compulsive disorder (OCD) identified a region on 9p24 with… (More)
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Highly Cited
2002
Highly Cited
2002
In patients suffering from temporal lobe epilepsy (TLE), increased extracellular glutamate levels in the epileptogenic… (More)
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Highly Cited
2001
Highly Cited
2001
Huntington's disease (HD) is a late-onset neurodegenerative disease for which the mutation is CAG/polyglutamine repeat expansion… (More)
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Highly Cited
1999
Highly Cited
1999
Na(+)-dependent transporters for glutamate exist on astrocytes (EAAT1 and EAAT2) and neurons (EAAT3). These transporters… (More)
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Highly Cited
1997
Highly Cited
1997
GLT-1, GLAST, and EAAC1 are high-affinity, Na(+)-dependent glutamate transporters identified in rat forebrain. The expression of… (More)
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Highly Cited
1996
Highly Cited
1996
SYNAPTIC transmission is commonly terminated by diffusion and reuptake of neurotransmitter from the synaptic cleft. Glutamate… (More)
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Highly Cited
1995
Highly Cited
1995
The pathogenesis of sporadic amyotrophic lateral sclerosis (ALS) is unknown, but defects in synaptosomal high-affinity glutamate… (More)
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Highly Cited
1994
Highly Cited
1994
The cellular and subcellular distributions of the glutamate transporter subtypes EAAC1, GLT-1, and GLAST in the rat CNS were… (More)
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Highly Cited
1994
Highly Cited
1994
Reuptake plays an important role in regulating synaptic and extracellular concentrations of glutamate. Three glutamate… (More)
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