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SLC1A1 gene

Known as: EAAC1, solute carrier family 1 member 1, SOLUTE CARRIER FAMILY 1 (NEURONAL/EPITHELIAL HIGH AFFINITY GLUTAMATE TRANSPORTER), MEMBER 1 
National Institutes of Health

Related topics

Related topics

1 relation
SLC1A7 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2010
2010
EAAC1 Gene Deletion Alters Zinc Homeostasis and Exacerbates Neuronal Injury after Transient Cerebral Ischemia
EAAC1 is a neuronal glutamate and cysteine transporter. EAAC1 uptake of cysteine provides substrate for neuronal glutathione… 
Highly Cited
2007
Highly Cited
2007
Prenatal exposure to the cannabinoid receptor agonist WIN 55,212-2 increases glutamate uptake through overexpression of GLT1 and EAAC1 glutamate transporter subtypes in rat frontal cerebral cortex
Highly Cited
2005
Highly Cited
2005
Evidence that protein kinase Cα interacts with and regulates the glial glutamate transporter GLT‐1
Many of the sodium‐dependent neurotransmitter transporters are rapidly (within minutes) regulated by protein kinase C (PKC), with… 
Highly Cited
2003
Highly Cited
2003
Phorbol Myristate Acetate-Dependent Interaction of Protein Kinase Cα and the Neuronal Glutamate Transporter EAAC1
Sodium-dependent transporters clear extracellular glutamate in the mammalian CNS. Activation of protein kinase C (PKC) rapidly… 
Highly Cited
2003
Highly Cited
2003
Is the Glutamate Residue Glu-373 the Proton Acceptor of the Excitatory Amino Acid Carrier 1?*
Glutamate transport by the neuronal excitatory amino acid carrier (EAAC1) is accompanied by the coupled movement of one proton… 
Highly Cited
2002
Highly Cited
2002
Long-term potentiation and contextual fear conditioning increase neuronal glutamate uptake
Induction and expression of long-term potentiation (LTP) in area CA1 of the hippocampus require the coordinated regulation of… 
2002
2002
Biosynthesis, Intracellular Targeting, and Degradation of the EAAC1 Glutamate/Aspartate Transporter in C6 Glioma Cells*
Rat C6 glioma cells were used as a model system to study the biosynthesis, intracellular targeting, and degradation of the EAAC1… 
Highly Cited
2000
Highly Cited
2000
On the Mechanism of Proton Transport by the Neuronal Excitatory Amino Acid Carrier 1
Uptake of glutamate from the synaptic cleft is mediated by high affinity transporters and is driven by Na+, K+, and H… 
Highly Cited
2000
Highly Cited
2000
Modulation of glutamate transporters (GLAST, GLT-1 and EAAC1) in the rat cerebellum following portocaval anastomosis
Highly Cited
1997
Highly Cited
1997
Hypoxia—ischemia causes abnormalities in glutamate transporters and death of astroglia and neurons in newborn striatum
The neonatal striatum degenerates after hypoxia–ischemia (H‐I). We tested the hypothesis that damage to astrocytes and loss of… 
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