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SLC18A2 gene

Known as: SLC18A2, VESICULAR AMINE TRANSPORTER 2, VMAT2 
This gene plays a role in neurotransmitter transport.
National Institutes of Health

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Related topics

8 relations
Homo sapiensIntracellular TransportLigand BindingMolecular Transport

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SLC18A2 wt Allele

Papers overview

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Highly Cited
2011
Highly Cited
2011
Differential expression of dopaminergic cell markers in the adult zebrafish forebrain
Although the simultaneous presence of tyrosine hydroxylase (TH), aromatic amino acid decarboxylase (AADC), dopamine transporter… 
Review
2009
Review
2009
Protective Actions of the Vesicular Monoamine Transporter 2 (VMAT2) in Monoaminergic Neurons
Vesicular monoamine transporters (VMATs) are responsible for the packaging of neurotransmitters such as dopamine, serotonin… 
Highly Cited
2008
Highly Cited
2008
VMAT2 and dopamine neuron loss in a primate model of Parkinson’s disease
We used positron emission tomography (PET) to measure the earliest change in dopaminergic synapses and glial cell markers in a… 
Highly Cited
2007
Highly Cited
2007
A rapid oxidation and persistent decrease in the vesicular monoamine transporter 2 after methamphetamine
Methamphetamine (METH) produces long‐term decreases in markers of dopamine (DA) terminals in animals and humans. A decrease in… 
Highly Cited
2007
Highly Cited
2007
Vesicular monoamine transporter 2 regulates the sensitivity of rat dopaminergic neurons to disturbed cytosolic dopamine levels
Highly Cited
2003
Highly Cited
2003
Expression of the Two Isoforms of the Vesicular Monoamine Transporter (VMAT1 and VMAT2) in the Endocrine Pancreas and Pancreatic Endocrine Tumors
The uptake of monoamines into the secretory granules of monoamine-storing neuroendocrine cells is mediated by vesicular monoamine… 
Highly Cited
2001
Highly Cited
2001
Mice with Very Low Expression of the Vesicular Monoamine Transporter 2 Gene Survive into Adulthood: Potential Mouse Model for Parkinsonism
ABSTRACT We have created a transgenic mouse with a hypomorphic allele of the vesicular monoamine transporter 2 (Vmat2) gene by… 
Highly Cited
1998
Highly Cited
1998
A Leucine-based Motif Mediates the Endocytosis of Vesicular Monoamine and Acetylcholine Transporters*
Specific transport proteins mediate the packaging of neurotransmitters into secretory vesicles and consequently require targeting… 
Highly Cited
1997
Highly Cited
1997
VMAT2 knockout mice: heterozygotes display reduced amphetamine-conditioned reward, enhanced amphetamine locomotion, and enhanced MPTP toxicity.
The brain vesicular monoamine transporter (VMAT2) pumps monoamine neurotransmitters and Parkinsonism-inducing dopamine… 
Highly Cited
1997
Highly Cited
1997
Knockout of the Vesicular Monoamine Transporter 2 Gene Results in Neonatal Death and Supersensitivity to Cocaine and Amphetamine
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