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SKA2 gene

Known as: SPINDLE- AND KINETOCHORE-ASSOCIATED COMPLEX, SUBUNIT 2, SPINDLE- AND KINETOCHORE-ASSOCIATED PROTEIN 2, FAMILY WITH SEQUENCE SIMILARITY 33, MEMBER A 
This gene plays a role in microtubule binding and chromosome segregation.
National Institutes of Health

Related topics

Related topics

7 relations
Cell Cycle ControlChromosome SegregationFAM8A1 geneMicrotubule Polymerization Process

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
PRR11 and SKA2 gene pair is overexpressed and regulated by p53 in breast cancer
Our previous study found that two novel cancer-related genes, PRR11 and SKA2, constituted a classic gene pair that was regulated… 
2018
2018
SKA2 mediates invasion and metastasis in human breast cancer via EMT.
Spindle and kinetochore‑associated protein 2 (SKA2) is essential for regulating the progression of mitosis. In recent years, SKA2… 
2018
2018
Long non-coding RNA SPRY4-IT1 promotes the proliferation and invasion of U251 cells through upregulation of SKA2.
The long non-coding RNA SPRY4-intronic transcript 1 (SPRY4-IT1) has been shown to promote the progression of cancer; however, the… 
Highly Cited
2016
Highly Cited
2016
SKA2 Methylation is Involved in Cortisol Stress Reactivity and Predicts the Development of Post-Traumatic Stress Disorder (PTSD) After Military Deployment
Genomic variation in the SKA2 gene has recently been identified as a promising suicide biomarker. In light of its role in… 
2016
2016
Discovery and replication of a peripheral tissue DNA methylation biosignature to augment a suicide prediction model
BackgroundSuicide is the second leading cause of death among adolescents in the USA, and rates are rising. Methods to identify… 
2016
2016
GLUCOCORTICOID RECEPTOR‐RELATED GENES: GENOTYPE AND BRAIN GENE EXPRESSION RELATIONSHIPS TO SUICIDE AND MAJOR DEPRESSIVE DISORDER
We tested the relationship between genotype, gene expression and suicidal behavior and major depressive disorder (MDD) in live… 
2016
2016
The Expression of the Suicide-Associated Gene SKA2 Is Decreased in the Prefrontal Cortex of Suicide Victims but Not of Nonsuicidal Patients
Background: Recent study of genome-wide DNA methylation profiling in the postmortem brain of suicidal and nonsuicidal subjects… 
2016
2016
Cyclic AMP responsive element-binding protein promotes renal cell carcinoma proliferation probably via the expression of spindle and kinetochore-associated protein 2
Emerging evidence shows that the aberrantly expressed cyclic AMP responsive element-binding protein (CREB) is associated with… 
Highly Cited
2015
Highly Cited
2015
Epigenetic and genetic variation at SKA2 predict suicidal behavior and post-traumatic stress disorder
Traumatic stress results in hypothalamic pituitary adrenal (HPA) axis abnormalities and an increased risk to both suicidal… 
Highly Cited
2008
Highly Cited
2008
Identification and functional analysis of SKA2 interaction with the glucocorticoid receptor
Glucocorticoid (GC) receptors (GRs) have profound anti-survival effects on human small cell lung cancer (SCLC). To explore the… 
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