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Prospective study of clinical predictors of suicidal acts after a major depressive episode in patients with major depressive disorder or bipolar disorder.
OBJECTIVE The authors investigated the predictive potential of a stress-diathesis model for suicidal behavior based on correlates of past suicidal acts. In this model, suicidal acts are precipitatedExpand
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Molecular aging in human prefrontal cortex is selective and continuous throughout adult life
BACKGROUND Aging leads to morphologic and functional changes in the brain and is associated with increased risk for psychiatric and neurological disorders. METHODS To identify age-relatedExpand
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Ketamine for Rapid Reduction of Suicidal Thoughts in Major Depression: A Midazolam-Controlled Randomized Clinical Trial.
OBJECTIVE Pharmacotherapy to rapidly relieve suicidal ideation in depression may reduce suicide risk. Rapid reduction in suicidal thoughts after ketamine treatment has mostly been studied in patientsExpand
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Sex differences in clinical predictors of suicidal acts after major depression: a prospective study.
OBJECTIVE Whether sex differences exist in clinical risk factors associated with suicidal behavior is unknown. The authors postulated that among men with a major depressive episode, aggression,Expand
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Clinical predictors of suicidal acts after major depression in bipolar disorder: a prospective study.
OBJECTIVE This study determined the clinical predictors of suicidal behavior during a 2-year follow-up of patients with bipolar disorder presenting with a major depressive episode (MDE). METHODExpand
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Attachment and social adjustment: relationships to suicide attempt and major depressive episode in a prospective study.
OBJECTIVE To study two aspects of interpersonal function - attachment security and social adjustment - in relation to suicide attempt and major depressive episode (MDE) during naturalistic follow-upExpand
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The relationship of aggression to suicidal behavior in depressed patients with a history of alcoholism.
BACKGROUND Alcoholism and depression are often comorbid. Studies suggest that depressed subjects with alcoholism have more chronic impairment and suicidal behavior than individuals with eitherExpand
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Parental care moderates the influence of MAOA-uVNTR genotype and childhood stressors on trait impulsivity and aggression in adult women
Objectives Adverse childhood experiences are associated with poor mental health outcomes, including vulnerability to mood disorders and/or antisocial behavior. A functional polymorphism in theExpand
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Moral or religious objections to suicide may protect against suicidal behavior in bipolar disorder.
OBJECTIVE Patients with bipolar disorder are prone to suicidal behavior, yet possible protective mechanisms are rarely studied. We investigated a possible protective role for moral or religiousExpand
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Omega-3 polyunsaturated essential fatty acid status as a predictor of future suicide risk.
OBJECTIVE Low levels of docosahexaenoic acid, a polyunsaturated fatty acid, and elevated ratios of omega-6/omega-3 fatty acids are associated with major depression and, possibly, suicidal behavior.Expand
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