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SK&F 86466

Known as: SK&F-86466, SKF 86466 
National Institutes of Health

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1 relation

Broader (1)

benalfocin

Papers overview

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2006
2006
Clonidine‐evoked respiratory effects in anaesthetized rats
The respiratory effects of stimulation of α2‐adrenergic receptors were studied in spontaneously breathing anaesthetized rats that… 
2001
2001
Modulation of ACh-induced currents in rat adrenal chromaffin cells by ligands of α2 adrenergic and imidazoline receptors
2001
2001
Analysis of ligand activation of α2-adrenoceptor subtypes under conditions of equal Gα protein stoichiometry
Abstract. Variations in the measurement of ligand's intrinsic activity between receptor subtypes is a common consequence of… 
2000
2000
Prototypical imidazoline-1 receptor ligand moxonidine activates alpha2-adrenoceptors in bulbospinal neurons of the RVL.
Moxonidine is an antihypertensive drug that lowers sympathetic vasomotor tone by stimulating either alpha2-adrenergic (alpha2-AR… 
2000
2000
Partial to complete antagonism by putative antagonists at the wild‐type α2C‐adrenoceptor based on kinetic analyses of agonist : antagonist interactions
Activation of the recombinant human α2C‐adrenoceptor (α2C AR) by (−)‐adrenaline in CHO‐K1 cells transiently co‐expressing a… 
Review
1999
Review
1999
Moxonidine: a new antiadrenergic antihypertensive agent.
Moxonidine is a centrally acting antihypertensive. Its action is mediated by imidazoline I1 receptors located in the rostral… 
1999
1999
A search for presynaptic imidazoline receptors at rabbit and rat noradrenergic neurones in the absence of α2-autoinhibition
Presynaptic, release-inhibiting imidazoline receptors have hitherto been detected mainly under conditions of ongoing α2… 
1990
1990
Antagonism of the hypothermic effect of clozapine in mice by centrally-active alpha 2-adrenergic antagonists and alpha 1-adrenergic agonists.
Hypothermia induced by either clozapine or clonidine in mice was blocked by the alpha 2-adrenergic antagonists yohimbine… 
1990
1990
Antagonism of the hypothermic effect of clozapine in mice by centrally-active α2-adrenergic antagonists and α1-adrenergic agonists
Hypothermia induced by either clozapine or clonidine in mice was blocked by the α2-adrenergic antagonists yohimbine, idazoxan, CH… 
1984
1984
The ocular hypotensive action of SK&F 86466 in the conscious rabbit.
SK&F 86466, 6-chloro-3-methyl-2, 3, 4, 5-tetrahydro-1H-3-benzazepine, a potent and selective competitive antagonist of the alpha… 
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