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SK&F 64139

Known as: SK&F-64139, SKF 64139 
 
National Institutes of Health

Papers overview

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2000
2000
It is well recognized that the reciprocal interaction established between the immune and neuroendocrine systems is crucial for… Expand
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1993
1993
Rat skeletal muscle contains two enzymes which can make epinephrine: phenylethanolamine N-methyltransferase (PNMT) and… Expand
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Highly Cited
1990
Highly Cited
1990
Interleukin-1 beta (IL-1 beta) is a potent ACTH secretagogue which activates the release of hypothalamic CRF but is unable to… Expand
1990
1990
Previous studies determined that iv nicotine stimulates ACTH secretion by acting on sites accessible from the fourth ventricle… Expand
1988
1988
1,2,3,4-Tetrahydroisoquinoline (THIQ) and aryl-substituted derivatives of THIQ are potent inhibitors of the enzyme that catalyzes… Expand
Highly Cited
1983
Highly Cited
1983
The preovulatory surge of luteinizing hormone reaches a maximum at 18.00 h on the day of pro-oestrus in female rats maintained… Expand
1983
1983
Two selective inhibitors of central epinephrine synthesis, LY 134046 and SKF 64139 (20 mg/kg, i.v.), gradually but markedly… Expand
1980
1980
The involvement of adrenal hormones as regulatory factors in maintaining physiological levels of tyrosine hydroxylase (TH) was… Expand
Highly Cited
1977
Highly Cited
1977
Abstract The effects of phenylethanolamine N-methyltransferase (PNMT) and dopamine-β-hydroxylase (DβH) inhibition on the… Expand
Highly Cited
1976
Highly Cited
1976
SK&F 64139 is a potent, reversible inhibitor of phenylethanolamine N-methyltransferase; its IC50 concentration in our standard… Expand