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SK&F 64139
Known as:
SK&F-64139
, SKF 64139
National Institutes of Health
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
1993
1993
Glucocorticoid induction of epinephrine synthesizing enzyme in rat skeletal muscle and insulin resistance.
B. Kennedy
,
H. Elayan
,
M. Ziegler
The Journal of clinical investigation
1993
Corpus ID: 207921
Rat skeletal muscle contains two enzymes which can make epinephrine: phenylethanolamine N-methyltransferase (PNMT) and…
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1993
1993
Glucocorticoid hypertension and nonadrenal phenylethanolamine N-methyltransferase.
B. Kennedy
,
H. Elayan
,
M. Ziegler
Hypertension
1993
Corpus ID: 15766068
Several drugs that block epinephrine synthesis by inhibiting phenylethanolamine N-methyltransferase (PNMT) lower blood pressure…
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Highly Cited
1990
Highly Cited
1990
The adrenocorticotropin response to interleukin-1 beta instilled into the rat median eminence depends on the local release of catecholamines.
S. Matta
,
J. Singh
,
R. Newton
,
B. Sharp
Endocrinology
1990
Corpus ID: 2648289
Interleukin-1 beta (IL-1 beta) is a potent ACTH secretagogue which activates the release of hypothalamic CRF but is unable to…
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1990
1990
Catecholamines mediate nicotine-induced adrenocorticotropin secretion via alpha-adrenergic receptors.
S. Matta
,
J. Singh
,
B. Sharp
Endocrinology
1990
Corpus ID: 1193098
Previous studies determined that iv nicotine stimulates ACTH secretion by acting on sites accessible from the fourth ventricle…
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Highly Cited
1983
Highly Cited
1983
Effects of manipulating catecholamines on the incidence of the preovulatory surge of luteinizing hormone and ovulation in the rat: Evidence for a necessary involvement of hypothalamic adrenaline in…
C. Coen
,
M. Coombs
Neuroscience
1983
Corpus ID: 7132440
1981
1981
Effect of adrenaline synthesis inhibition on brain noradrenaline neurons in locus coeruleus
G. Engberg
,
M. Elam
,
T. Svensson
Brain Research
1981
Corpus ID: 23115224
1981
1981
Properties of 8,9-dichloro-2,3,4,5-tetrahydro-1H-2-benzazepine, an inhibitor of norepinephrine N-methyltransferase.
R. Fuller
,
S. Hemrick-Luecke
,
R. E. Toomey
,
J. Horng
,
R. Ruffolo
,
B. Molloy
Biochemical pharmacology
1981
Corpus ID: 9113630
1980
1980
Adrenal influence on tyrosine hydroxylase activity in superior cervical ganglion
K. Markey
,
P. Y. Sze
Brain Research
1980
Corpus ID: 2587513
Highly Cited
1977
Highly Cited
1977
Effect of phenylethanolamine N-methyltransferase and dopamine-beta-hydroxylase inhibition on epinephrine levels in the brain.
A. Sauter
,
J. Y. Lew
,
Y. Baba
,
M. Goldstein
Life sciences
1977
Corpus ID: 41486158
Highly Cited
1976
Highly Cited
1976
Studies on adrenal phenylethanolamine N- methyltransferase (PNMT) with S K & F 64139, a selective inhibitor.
R. Pendleton
,
C. Kaiser
,
G. Gessner
The Journal of pharmacology and experimental…
1976
Corpus ID: 32062180
SK&F 64139 is a potent, reversible inhibitor of phenylethanolamine N-methyltransferase; its IC50 concentration in our standard…
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