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The sigma receptor 1 (σR1) has been shown to modulate the activity of several voltage- and ligand-gated channels. Using patch… Expand σ Receptors, once considered a class of opioid receptors, are now regarded as a unique class of receptors that contain binding… Expand Abstract: To evaluate the possibility of pharmacologically distinct N‐methyl‐D‐aspartate (NMDA) receptor subtypes, quantitative… Expand The sigma receptor is a neuronal substrate that binds several psychoactive compounds. These include cocaine, some steroids… Expand The functional mechanisms of noncompetitive blockade of the nicotinic acetylcholine receptor from the BC3H-1 cell line were… Expand The effects of iontophoretically applied opiates were tested on 24 spinothalamic tract cells in 12 anesthetized monkeys. The… Expand A portion of the specific binding of tritiated SKF-10047 to the guinea-pig brain suspension of the particulate fraction is not… Expand Phencyclidine (PCP) displaceable binding of 3H-PCP to glass-fiber filters was eliminated and total binding markedly reduced by… Expand In rats implanted with chronic catheters in the spinal subarachnoid space, intrathecal injections of SKF 10047 and dynorphin did… Expand Cholinergic neurons which possess mu and delta receptors and/or which are regulated by neurons possessing these receptors, do not… Expand