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SIX3 gene

Known as: SINE OCULIS HOMEOBOX, DROSOPHILA, HOMOLOG OF, 3, SIX Homeobox 3 Gene, SIX homeobox 3 
This gene plays a role in retinal development.
National Institutes of Health

Related topics

Related topics

8 relations
Biologic DevelopmentCell Differentiation processHOLOPROSENCEPHALY 2 (disorder)Homo sapiens

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
A novel long noncoding RNA lncWDR26 suppresses the growth and metastasis of hepatocellular carcinoma cells through interaction with SIX3.
Hepatocellular carcinoma (HCC) is the third leading cause of cancer-related deaths worldwide. Long noncoding RNAs (lncRNAs) are… 
2018
2018
SIX3 deletions and incomplete penetrance in families affected by holoprosencephaly
Holoprosencephaly (HPE) is failure of the forebrain to divide completely during embryogenesis. Incomplete penetrance has not been… 
2017
2017
Epigenetically controlled Six3 expression regulates glioblastoma cell proliferation and invasion alongside modulating the activation levels of WNT pathway members
Glioma is the most common primary brain tumor in adults. Six3 is a human homologue of the highly conserved sine oculis gene… 
2015
2015
Genotypic and phenotypic variation in six patients with solitary median maxillary central incisor syndrome
Solitary Median Maxillary Central Incisor occurs in 1 of 50,000 live births. It is the mildest manifestation of the… 
Review
2010
Review
2010
Autoregulatory binding sites in the zebrafish six3a promoter region define a new recognition sequence for Six3 proteins
The homeodomain (HD) transcription factor Six3, which is a member of the Six/Sine oculis family, is essential for development of… 
2010
2010
Focus on molecules: Six3--master or apprentice?
2009
2009
Holoprosencephaly, ectrodactyly, and bilateral cleft of lip and palate: Exclusion of SHH, TGIF, SIX3, GLI2, TP73L, and DHCR7 as candidate genes
We describe a Brazilian boy with semilobar holoprosencephaly, ectrodactyly, bilateral cleft of lip and palate, and severe mental… 
2003
2003
The homeotic protein Six3 is a coactivator of the nuclear receptor NOR-1 and a corepressor of the fusion protein EWS/NOR-1 in human extraskeletal myxoid chondrosarcomas.
Nuclear receptors represent a large family of transcription factors involved in development, differentiation, homeostasis, and… 
2002
2002
Molecular diagnosis of a novel heterozygous 268C→T (R90C) mutation in TGIF gene in a fetus with holoprosencephaly and premaxillary agenesis
We report the sonographic diagnosis and molecular analysis of holoprosencephaly (HPE) and premaxillary agenesis in a second… 
2000
2000
Characterisation of the promoter region of the zebrafish six7 gene.
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