HOLOPROSENCEPHALY 2 (disorder)
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Mice heterozygous for the Otx2 mutation display a craniofacial malformation, known as otocephaly or agnathia-holoprosencephaly… Expand Hypericum perforatum extracts (HPE) inhibit ethanol intake in rats. Hypericin and hyperforin have been proposed as major active… Expand Holoprosencephaly (HPE) is a severe brain malformation which results from incomplete cleavage of the forebrain during early… Expand Holoprosencephaly (HPE) is a common, severe malformation of the brain that involves separation of the central nervous system into… Expand The Drosophila gene sine oculis (so), a nuclear homeoprotein that is required for eye development, has several homologues in… Expand Holoprosencephaly (HPE) is a common developmental defect involving the brain and face in humans. Cytogenetic deletions in… Expand The Drosophila sine oculis homeobox-containing gene is known to play an essential role in controlling the initial events of… Expand A 2-year-old girl with alobar holoprosencephaly associated with facial abnormalities, central diabetes insipidus, and a neuronal… Expand Holoprosencephaly (HPE) is a common malformation of the developing forebrain and midface characterized by incomplete penetrance… Expand Two stillborn sisters had characteristics of both agnathia and holoprosencephaly. Familial occurrence implies that agnathia… Expand