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SIRT1 gene

Known as: SIR2L1, SIR2, S. CEREVISIAE, HOMOLOG-LIKE 1, SIRT1 
This gene may be involved in the regulation of protein acetylation.
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2019
Review
2019
The rising incidence of type 2 diabetes mellitus (T2DM) is a major public health concern, and novel therapeutic strategies to… Expand
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Review
2019
Review
2019
Cardiovascular and metabolic diseases (CVMD) are the leading causes of death worldwide, underscoring the urgent necessity to… Expand
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Review
2018
Review
2018
SIGNIFICANCE Oxidative stress represents the common hallmark of pathological conditions associated with cardiovascular disease… Expand
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Review
2018
Review
2018
Alzheimer's disease (AD) is a progressive and neurodegenerative disorder of the cortex and hippocampus, which eventually leads to… Expand
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Review
2017
Review
2017
Forkhead box class O 3a (FOXO3a) is a transcription factor that has emerged as being a tumor suppressor and longevity factor. The… Expand
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Review
2017
Review
2017
The prevalence of diabetes mellitus (DM) has been increasing worldwide. Diabetic cardiomyopathy (DCP) is the major risk for… Expand
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Highly Cited
2008
Highly Cited
2008
The mammalian circadian timing system is composed of a central pacemaker in the suprachiasmatic nucleus of the brain that… Expand
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Highly Cited
2006
Highly Cited
2006
Diminished mitochondrial oxidative phosphorylation and aerobic capacity are associated with reduced longevity. We tested whether… Expand
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Highly Cited
2004
Highly Cited
2004
NF‐κB is responsible for upregulating gene products that control cell survival. In this study, we demonstrate that SIRT1, a… Expand
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Highly Cited
2004
Highly Cited
2004
Calorie restriction extends lifespan in organisms ranging from yeast to mammals. In yeast, the SIR2 gene mediates the life… Expand
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