Epigenetic Silencing

This process is initiated by the formation of heterochromatin which ultimately leads to transcriptional inactivation or silencing. Once formed… (More)
National Institutes of Health

Papers overview

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Highly Cited
2011
Highly Cited
2011
Vernalization is an environmentally-induced epigenetic switch in which winter cold triggers epigenetic silencing of floral… (More)
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Highly Cited
2008
Highly Cited
2008
Altered expression of microRNA (miRNA) is strongly implicated in cancer, and recent studies have shown that, in cancer… (More)
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Highly Cited
2008
Highly Cited
2008
Intrauterine growth retardation (IUGR) has been linked to the onset of diseases in adulthood, including type 2 diabetes, and has… (More)
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Highly Cited
2008
Highly Cited
2008
Vernalization, the acceleration of flowering by winter, involves cold-induced epigenetic silencing of Arabidopsis FLC. This… (More)
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Review
2007
Review
2007
During development, cells start in a pluripotent state, from which they can differentiate into many cell types, and progressively… (More)
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Highly Cited
2007
Highly Cited
2007
The conversion of a normal cell to a cancer cell occurs in several steps and typically involves the activation of oncogenes and… (More)
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Highly Cited
2006
Highly Cited
2006
Phosphatase and tensin homologue deleted from chromosome 10 (PTEN) seems to be an important tumor suppressor gene in melanoma… (More)
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Highly Cited
2004
Highly Cited
2004
To ensure flowering in favourable conditions, many plants flower only after an extended period of cold, namely winter. In… (More)
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Highly Cited
2002
Highly Cited
2002
T lymphocytes differentiate in discrete stages within the thymus. Immature thymocytes lacking CD4 and CD8 coreceptors… (More)
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Review
1998
Review
1998
Nuclear processes that silence plant transgenes are being revealed by analyses of natural triggers of epigenetic modifications… (More)
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