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Hypermethylation

Hypermethylation appears to be a controlled, epigenetic, heritable, and aberrant DNA methylation reaction on gene promoter regions and CpG islands… 
National Institutes of Health

Papers overview

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Review
2010
Review
2010
The assessment of DNA had demonstrated altered methylation in malignant compared to benign breast tissue. The purpose of our… 
Highly Cited
2003
Highly Cited
2003
Promoter hypermethylation represents a primary mechanism in the inactivation of tumor suppressor genes during tumorigenesis. To… 
Highly Cited
2001
Highly Cited
2001
Aberrant methylation of CpG islands within promoter regions is associated with transcriptional inactivation of various tumor… 
Highly Cited
2000
Highly Cited
2000
The p16INK4A gene encodes 2 cell cycle regulator proteins, p16 and p14ARF, by alternative splicing. This genetic locus also… 
Highly Cited
2000
Highly Cited
2000
Hypermethylation of p16 has been detected frequently in a variety of cancer cells and is known to repress the level of p16… 
Review
2000