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Hypermethylation

Hypermethylation appears to be a controlled, epigenetic, heritable, and aberrant DNA methylation reaction on gene promoter regions and CpG islands… 
National Institutes of Health

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Epigenetic Silencing

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2014
Highly Cited
2014
The acquisition of cancer stem cell-like properties and neoplastic transformation of human keratinocytes induced by arsenite involves epigenetic silencing of let-7c via Ras/NF-κB.
Highly Cited
2013
Highly Cited
2013
Re: Epigenetic disruption of the PIWI pathway in human spermatogenic disorders.
Review
2010
Review
2010
Quantitative evaluation of DNA hypermethylation in malignant and benign breast tissue and fluids
The assessment of DNA had demonstrated altered methylation in malignant compared to benign breast tissue. The purpose of our… 
Highly Cited
2003
Highly Cited
2003
Promoter hypermethylation of multiple genes in astrocytic gliomas.
Promoter hypermethylation represents a primary mechanism in the inactivation of tumor suppressor genes during tumorigenesis. To… 
Review
2002
Review
2002
DNA methylation changes in leukaemia.
Highly Cited
2001
Highly Cited
2001
Promoter hypermethylation of MGMT is associated with protein loss in gastric carcinoma
Aberrant methylation of CpG islands within promoter regions is associated with transcriptional inactivation of various tumor… 
Highly Cited
2000
Highly Cited
2000
p16 is a major inactivation target in hepatocellular carcinoma
The p16INK4A gene encodes 2 cell cycle regulator proteins, p16 and p14ARF, by alternative splicing. This genetic locus also… 
Highly Cited
2000
Highly Cited
2000
Correlation of p16 Hypermethylation with p16 Protein Loss in Sporadic Gastric Carcinomas
Hypermethylation of p16 has been detected frequently in a variety of cancer cells and is known to repress the level of p16… 
Review
2000
Review
2000
Genetic and epigenetic alterations in carcinogenesis.
Highly Cited
1965
Highly Cited
1965
Synthesis and transmethylation of DNA in polyoma-infected cultures.
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