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Hypermethylation
Hypermethylation appears to be a controlled, epigenetic, heritable, and aberrant DNA methylation reaction on gene promoter regions and CpG islands…
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National Institutes of Health
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Related topics
Related topics
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Epigenetic Silencing
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2014
Highly Cited
2014
The acquisition of cancer stem cell-like properties and neoplastic transformation of human keratinocytes induced by arsenite involves epigenetic silencing of let-7c via Ras/NF-κB.
Rongrong Jiang
,
Yuan Li
,
+6 authors
Qizhan Liu
Toxicology Letters
2014
Corpus ID: 24313837
Highly Cited
2013
Highly Cited
2013
Re: Epigenetic disruption of the PIWI pathway in human spermatogenic disorders.
C. Niederberger
Journal of Urology
2013
Corpus ID: 12472549
Review
2010
Review
2010
Quantitative evaluation of DNA hypermethylation in malignant and benign breast tissue and fluids
Weizhu Zhu
,
Wenyi Qin
,
J. Hewett
,
E. Sauter
International Journal of Cancer
2010
Corpus ID: 24567225
The assessment of DNA had demonstrated altered methylation in malignant compared to benign breast tissue. The purpose of our…
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Highly Cited
2003
Highly Cited
2003
Promoter hypermethylation of multiple genes in astrocytic gliomas.
P. González‐Gómez
,
M. Bello
,
+7 authors
J. Rey
International Journal of Oncology
2003
Corpus ID: 23125100
Promoter hypermethylation represents a primary mechanism in the inactivation of tumor suppressor genes during tumorigenesis. To…
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Review
2002
Review
2002
DNA methylation changes in leukaemia.
John R. Melki
,
S. Clark
Seminars in Cancer Biology
2002
Corpus ID: 24748226
Highly Cited
2001
Highly Cited
2001
Promoter hypermethylation of MGMT is associated with protein loss in gastric carcinoma
N. Oue
,
H. Shigeishi
,
+4 authors
W. Yasui
International Journal of Cancer
2001
Corpus ID: 20755946
Aberrant methylation of CpG islands within promoter regions is associated with transcriptional inactivation of various tumor…
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Highly Cited
2000
Highly Cited
2000
p16 is a major inactivation target in hepatocellular carcinoma
M. Baek
,
Z. Piao
,
+6 authors
Hoguen Kim
Cancer
2000
Corpus ID: 19597121
The p16INK4A gene encodes 2 cell cycle regulator proteins, p16 and p14ARF, by alternative splicing. This genetic locus also…
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Highly Cited
2000
Highly Cited
2000
Correlation of p16 Hypermethylation with p16 Protein Loss in Sporadic Gastric Carcinomas
Y. Shim
,
G. Kang
,
J. Ro
Laboratory Investigation
2000
Corpus ID: 8380000
Hypermethylation of p16 has been detected frequently in a variety of cancer cells and is known to repress the level of p16…
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Review
2000
Review
2000
Genetic and epigenetic alterations in carcinogenesis.
Takashi Sugimura
,
Toshikazu Ushijima
Mutation research
2000
Corpus ID: 9663151
Highly Cited
1965
Highly Cited
1965
Synthesis and transmethylation of DNA in polyoma-infected cultures.
E. Winocour
,
A. Kaye
,
V. Stollar
Virology
1965
Corpus ID: 5090183
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