• Publications
  • Influence
Relation between microRNA expression and progression and prognosis of gastric cancer: a microRNA expression analysis.
BACKGROUND Analyses of microRNA expression profiles have shown that many microRNAs are expressed aberrantly and correlate with tumorigenesis, progression, and prognosis of various haematological andExpand
  • 739
  • 26
Hypoxia-inducible factor-1alpha polymorphisms associated with enhanced transactivation capacity, implying clinical significance.
Hypoxia-inducible factor-1 (HIF-1) is a pivotal factor that regulates cellular responses to hypoxia and is presumably linked to regulation of angiogenesis and tumor growth. We assessed the differenceExpand
  • 221
  • 21
  • PDF
Mesenchymal stem cells enhance growth and metastasis of colon cancer
Recently, mesenchymal stem cells (MSCs) were reported to migrate to tumor stroma as well as injured tissue. We examined the role of human MSCs in tumor stroma using an orthotopic nude mice model ofExpand
  • 262
  • 8
Identification of nectin-4 oncoprotein as a diagnostic and therapeutic target for lung cancer.
Gene expression profile analysis of lung cancers revealed the transactivation of an immunoglobulin-like molecule Nectin-4 in the majority of non-small cell lung cancers (NSCLC). ImmunohistochemicalExpand
  • 142
  • 8
  • PDF
Serum olfactomedin 4 (GW112, hGC‐1) in combination with Reg IV is a highly sensitive biomarker for gastric cancer patients
Gastric cancer (GC) is 1 of the most common human cancers. Early detection remains the most promising approach to improving long‐term survival of patients with GC. We previously performed SerialExpand
  • 91
  • 8
Energy budget of a small Cetacean, the harbour Porpoise, Phocoena Phocoena (L.)
Abstract The objective of this study was to assemble the components of an energy budget for the harbour porpoise in the western Bay of Fundy, Canada. The annual energetic requirements for basal andExpand
  • 69
  • 8
RET/PTC rearrangements preferentially occurred in papillary thyroid cancer among atomic bomb survivors exposed to high radiation dose.
A major early event in papillary thyroid carcinogenesis is constitutive activation of the mitogen-activated protein kinase signaling pathway caused by alterations of a single gene, typicallyExpand
  • 124
  • 7
  • PDF
Systematic search for gastric cancer-specific genes based on SAGE data: melanoma inhibitory activity and matrix metalloproteinase-10 are novel prognostic factors in patients with gastric cancer
Gastric cancer (GC) is one of the most common malignancies worldwide. Genes expressed only in cancer tissue will be useful molecular markers for diagnosis and may also be good therapeutic targets.Expand
  • 149
  • 7
Expression of cancer stem cell markers ALDH1, CD44 and CD133 in primary tumor and lymph node metastasis of gastric cancer
Gastric cancer (GC) is one of the most common malignancies worldwide. Recently, cancer stem cells (CSCs) in tumors were found to possess the ability to sustain tumor self‐renewal, initiate tumorExpand
  • 153
  • 7
A single nucleotide polymorphism in the MMP-1 promoter is correlated with histological differentiation of gastric cancer
AbstractPurposeMatrix metalloproteinase-1 (MMP-1) plays a key role in cancer invasion and metastasis by degradation of extracellular matrix (ECM) and basement membrane barriers. The 1G/2G singleExpand
  • 41
  • 7