Sirtuin 1

Known as: Silent Mating Type Information Regulation 2 Homolog 1, Sirtuin 1 [Chemical/Ingredient] 
A sirtuin family member found primarily in the CELL NUCLEUS. It is an NAD-dependent deacetylase with specificity towards HISTONES and a variety of… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

2005-2017
010203020052017

Papers overview

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2014
2014
BACKGROUND The angiotensin-converting enzyme 2 and angiotensin-(1-7) (Ang 1-7)/MasR (Mas receptor) axis are emerging as a key… (More)
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Highly Cited
2013
Highly Cited
2013
BACKGROUND AND PURPOSE Sirtuin 1 (SIRT1) is a member of NAD+-dependent protein deacetylases implicated in a wide range of… (More)
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Highly Cited
2012
Highly Cited
2012
Glomerular podocytes are highly specialized epithelial cells whose injury in glomerular diseases causes proteinuria. Since… (More)
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2012
2012
Epithelial-mesenchymal transition (EMT) plays a pivotal role in the pathogenesis of renal tubulointerstitial fibrosis. We… (More)
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Highly Cited
2011
Highly Cited
2011
OBJECTIVE Stroke is a leading cause of mortality and disability. Nicotinamide phosphoribosyltransferase (Nampt) is the rate… (More)
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2011
2011
Numerous studies indicate that Sirtuin 1 (SIRT1), a mammalian nicotinamide adenine dinucleotide (NAD(+))-dependent histone… (More)
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2011
2011
Silent mating type information regulation 2 homolog 1 (SIRT1) plays a critical role in reactive oxygen species-triggered… (More)
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2011
2011
Silent mating type information regulation 2 homolog 1 (SIRT1) is a multifaceted, nicotinamide adenine dinucleotide-dependent… (More)
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Highly Cited
2009
Highly Cited
2009
Sirtuin 1 (Sirt1) and Sirtuin 2 (Sirt2) belong to the family of NAD+ (nicotinamide adenine dinucleotide-positive)-dependent class… (More)
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2009
2009
Sirtuin 1 is a member of the sirtuin family of protein deacetylases, which have attracted considerable attention as mediators of… (More)
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