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Sirtuin 1

Known as: Silent Mating Type Information Regulation 2 Homolog 1, Sirtuin 1 [Chemical/Ingredient] 
A sirtuin family member found primarily in the CELL NUCLEUS. It is an NAD-dependent deacetylase with specificity towards HISTONES and a variety of… 
National Institutes of Health

Related topics

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In BloodProcess of secretionantagonists & inhibitorsaspects of radiation effects

Broader (1)

SIRT1 gene

Narrower (2)

SIRT1 protein, humanSirt1 protein, rat

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Clinicopathological and predictive significance of SIRT1 and peroxisome proliferator-activated receptor gamma in esophageal squamous cell carcinoma: The correlation with EGFR and Survivin.
Review
2017
Review
2017
Harnessing the Power of SIRT1 and Non-coding RNAs in Vascular Disease.
Noncommunicable diseases (NCDs) contribute to a significant amount of disability and death in the world. Of these disorders… 
2017
2017
Ultraviolet B inhibition of DNMT1 activity via AhR activation dependent SIRT1 suppression in CD4+ T cells from systemic lupus erythematosus patients.
2017
2017
Korean red ginseng improves testicular ineffectiveness in aging rats by modulating spermatogenesis-related molecules
2016
2016
Association of SIRT1 and HMGA1 expression in non-small cell lung cancer.
The roles of Silent mating type information regulation 2 homolog 1 (SIRT1) and High mobility group A1 (HMGA1) in human diseases… 
2015
2015
SIRT1 attenuates PAF-induced MMP-2 production via down-regulation of PAF receptor expression in vascular smooth muscle cells.
2014
2014
Preferential expression of PAPPA in human preadipocytes from omental fat.
Fat distribution differs between individuals, and those with visceral fat predominance develop metabolic profiles that increase… 
2014
2014
Morphoproteomics identifies constitutive activation of the mTORC2/Akt and NF-κB pathways and expressions of IGF-1R, Sirt1, COX-2, and FASN in peripheral T-cell lymphomas: pathogenetic implications…
BACKGROUND Gaining a better understanding of the molecular circuitries and pathways implicated in the malignant growth and… 
2014
2014
Central Sirt1 regulates body weight and energy expenditure along with the POMC-derived peptide α-MSH and the processing enzyme CPE production in diet-induced obese male rats.
In the periphery, the nutrient-sensing enzyme Sirtuin 1 (silent mating type information regulation 2 homolog 1 [Sirt1]) reduces… 
2007
2007
Enhancing cell longevity for cosmetic application: a complementary approach.
BACKGROUND AND OBJECTIVES Cell longevity is linked to sirtuins (silent information regulators), which belong to a family of… 
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