Skip to search formSkip to main contentSkip to account menu

SIRT1 protein, human

Known as: SIR2-Like Protein 1, sirtuin 1, human, Regulatory Protein SIR2 Homolog 1 
NAD-dependent protein deacetylase sirtuin-1 (747 aa, ~82 kDa) is encoded by the human SIRT1 gene. This protein may be involved in protein… 
National Institutes of Health

Related topics

Related topics

9 relations
DNA RepairDNA ReplicationDeacetylationEnzyme Gene

Narrower (1)

NAD-Dependent Deacetylase Sirtuin-3, Mitochondrial

Broader (1)

Sirtuin 1

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
Comparison of apoptosis between bovine subcutaneous and intramuscular adipocytes by resveratrol via SIRT1
Abstract A better understanding of the differential mechanisms regulating the deposition and release of fat between intramuscular… 
2019
2019
A synthetic non-histone substrate to study substrate targeting by the Gcn5 HAT and sirtuin HDACs
Gcn5 and sirtuins are highly conserved histone acetyltransferase (HAT) and histone deacetylase (HDAC) enzymes that were first… 
2018
2018
Melatonin Ameliorates Busulfan-Induced Spermatogonial Stem Cell Oxidative Apoptosis in Mouse Testes
Abstract Aims: Many men endure immunosuppressive or anticancer treatments that contain alkylating agents before the age of sexual… 
2018
2018
Involvement of spinal SIRT1 in development of chronic constriction injury induced neuropathic pain in rats.
It is known that the epigenetic process of histone acetylation is involved in the neuropathic pain. The aim of this study was to… 
2017
2017
MicroRNA-138 inhibits cell proliferation in hepatocellular carcinoma by targeting Sirt1.
MicroRNAs (miRNAs) are a family of small, non‑coding RNA molecules that are highly conserved across species and function as… 
2015
2015
Inhibition of microRNA-9-3p reduces lipid accumulation in HepG2 cells by targeting the expression of sirtuin type 1.
Type 2 diabetes mellitus (T2DM) is a complex metabolic disorder caused by the interaction of environmental factors and multiple… 
2014
2014
Expression of c-Myc, SIRT1 and acetyl-p53 in breast carcinoma and prognostic significance
Objective: To study the correlation between c-Myc, Sirtuin type 1 (SIRT1), acetyl-p53 protein and the prognosis of breast… 
Review
2014
Review
2014
Natural autophagy regulators in cancer therapy: a review
Autophagy is a complicated self-eating response of cells to external or internal stimuli. This process involves cellular… 
2014
2014
Expression and significance of sirtuin type 1 and forkhead box M1 in pathological scar
Objective To study the expression of sirtuin type 1 (SIRT1) and forkhead box M1 (FOXM1) gene in the pathological scars and to… 
2010
2010
Growth factor deprivation induces cytosolic translocation of SIRT1
Sirtuin type 1 (SIRT1), a NAD+-dependent histone deacetylases, plays a critical role in cellular senescence, aging and longevity… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)