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SIK2 gene
Known as:
salt inducible kinase 2
, Salt-Inducible Kinase 2 Gene
, LOH11CR1I
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This gene plays a role in both signal transduction and spindle formation.
National Institutes of Health
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Related topics
Related topics
6 relations
Broader (1)
Genes
Phosphorylation
Serine/Threonine Phosphorylation
Signal Transduction
salt-inducible kinase-2, human
Narrower (1)
SIK2 wt Allele
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
Long non-coding RNA UCA1 promotes the progression of paclitaxel resistance in ovarian cancer by regulating the miR-654-5p/SIK2 axis.
Z-Y Li
,
X.-L. Wang
,
+4 authors
L. Zheng
European Review for Medical and Pharmacological…
2020
Corpus ID: 211026190
OBJECTIVE Ovarian cancer (OC) is a common tumor in women, and the development of chemoresistance is the major obstacle to its…
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2020
2020
Advances in Cellular Target Engagement and Target Deconvolution
M. Main
,
Andrew X. Zhang
SLAS discovery : advancing life sciences R & D
2020
Corpus ID: 210831019
Proof of target engagement, the interaction between a lead molecule and its protein target, is a critical determinant of success…
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2019
2019
High-Throughput Implementation of the NanoBRET Target Engagement Intracellular Kinase Assay to Reveal Differential Compound Engagement by SIK2/3 Isoforms
H. Jin
,
Y. Tudor
,
+4 authors
A. Symons
SLAS discovery : advancing life sciences R & D
2019
Corpus ID: 209408536
The real-time quantification of target engagement (TE) by small-molecule ligands in living cells remains technically challenging…
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2019
2019
Insulin induces Thr484 phosphorylation and stabilization of SIK2 in adipocytes.
Johanna Säll
,
Florentina Negoita
,
+8 authors
Olga Göransson
Cellular Signalling
2019
Corpus ID: 58659432
2018
2018
Suppression of gluconeogenic gene transcription by SIK1-induced ubiquitination and degradation of CRTC1.
Weixi Gao
,
H. Tang
,
Yun Cheng
,
Chi-Ping Chan
,
Chi-Ping Chan
,
D. Jin
Biochimica et Biophysica Acta. Gene Regulatory…
2018
Corpus ID: 3883683
2015
2015
AISLADOS PROTEÍNICOS DE GRANOS ALTOANDINOS CHENOPODIACEAS; QUINUA “CHENOPODIUM QUINOA” – CAÑAHUA “CHENOPODIUM PALLIDICAULE” POR PRECIPITACIÓN ISOELÉCTRICA
J. Carlos.
,
A. Callisaya
,
J. Antonio
,
K. Alvarado
2015
Corpus ID: 101453323
The quinoa (Chenopodium Quinoa Willd) and the canihua (Chenopodium Pallidicaule Aellen), pseudocereals of the region of the Andes…
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2015
2015
Practical Experience of the Application of a Weighted Burden Test to Whole Exome Sequence Data for Obesity and Schizophrenia
D. Curtis
Annals of Human Genetics
2015
Corpus ID: 5754393
For biological and statistical reasons it makes sense to combine information from variants at the level of the gene. One may wish…
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2014
2014
SIK2 regulates insulin secretion
Bengt-Frederik Belgardt
,
M. Stoffel
Nature Cell Biology
2014
Corpus ID: 28625018
Correct regulation of insulin secretion by the pancreas is crucial for organismal function and survival. The AMPK-related kinase…
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2004
2004
Identification and characterization of human FOXN5 and rat Foxn5 genes in silico.
Masuko Katoh
,
M. Katoh
International Journal of Oncology
2004
Corpus ID: 10679761
Forkhead-box (FOX) genes are implicated in embryogenesis through transcriptional regulation depending on SHH-GLI pathway, TGF…
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2000
2000
The new serine-threonine kinase, Qik, is a target of the Qin oncogene.
Yu Xia
,
Zhihong Zhang
,
Ulrich Kruse
,
Peter K. Vogt
,
Jian Li
Biochemical and Biophysical Research…
2000
Corpus ID: 5807281
The winged helix transcription factor Qin is the avian homolog of the mammalian brain factor 1 (BF-1) and has the potential to…
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