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SIK2 gene

Known as: salt inducible kinase 2, Salt-Inducible Kinase 2 Gene, LOH11CR1I 
This gene plays a role in both signal transduction and spindle formation.
National Institutes of Health

Related topics

Related topics

6 relations

Broader (1)

Genes
PhosphorylationSerine/Threonine PhosphorylationSignal Transductionsalt-inducible kinase-2, human

Narrower (1)

SIK2 wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
Long non-coding RNA UCA1 promotes the progression of paclitaxel resistance in ovarian cancer by regulating the miR-654-5p/SIK2 axis.
OBJECTIVE Ovarian cancer (OC) is a common tumor in women, and the development of chemoresistance is the major obstacle to its… 
2019
2019
High-Throughput Implementation of the NanoBRET Target Engagement Intracellular Kinase Assay to Reveal Differential Compound Engagement by SIK2/3 Isoforms
The real-time quantification of target engagement (TE) by small-molecule ligands in living cells remains technically challenging… 
2019
2019
Insulin induces Thr484 phosphorylation and stabilization of SIK2 in adipocytes.
2018
2018
Suppression of gluconeogenic gene transcription by SIK1-induced ubiquitination and degradation of CRTC1.
2014
2014
SIK2 regulates insulin secretion
Correct regulation of insulin secretion by the pancreas is crucial for organismal function and survival. The AMPK-related kinase… 
2010
2010
Amplification at 11q23 targets protein kinase SIK2 in diffuse large B-cell lymphoma
In diffuse large B-cell lymphoma (DLBCL), several recurrent chromosomal aberrations have been described where the presumed target… 
2010
2010
Can oral bisphosphonates really reduce the risk of breast cancer in healthy women?
cisplatin-paclitaxel versus cisplatin-cyclophosphamide in women with advanced epithelial ovarian cancer: Three year results. J… 
Review
2004
Review
2004
Salt-inducible kinase in steroidogenesis and adipogenesis
2004
2004
Identification and characterization of human FOXN5 and rat Foxn5 genes in silico.
Forkhead-box (FOX) genes are implicated in embryogenesis through transcriptional regulation depending on SHH-GLI pathway, TGF… 
2000
2000
The new serine-threonine kinase, Qik, is a target of the Qin oncogene.
The winged helix transcription factor Qin is the avian homolog of the mammalian brain factor 1 (BF-1) and has the potential to… 
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