SHANK3 gene

Known as: PSAP2, SH3 and multiple ankyrin repeat domains 3, SPANK-2 
This gene may play a role in neuronal function.
National Institutes of Health

Topic mentions per year

Topic mentions per year

2003-2017
010203020032017

Papers overview

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Highly Cited
2013
Highly Cited
2013
Phelan-McDermid syndrome (PMDS) is a complex neurodevelopmental disorder characterized by global developmental delay, severely… (More)
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Highly Cited
2012
Highly Cited
2012
Genetic mutations of SHANK3 have been reported in patients with intellectual disability, autism spectrum disorder (ASD) and… (More)
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Highly Cited
2011
Highly Cited
2011
Autism spectrum disorders (ASDs) comprise a range of disorders that share a core of neurobehavioural deficits characterized by… (More)
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Highly Cited
2011
Highly Cited
2011
SHANK3 is a synaptic scaffolding protein enriched in the postsynaptic density (PSD) of excitatory synapses. Small microdeletions… (More)
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Highly Cited
2010
Highly Cited
2010
BACKGROUND SHANK3 is a protein in the core of the postsynaptic density (PSD) and has a critical role in recruiting many key… (More)
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Highly Cited
2010
Highly Cited
2010
Schizophrenia likely results from poorly understood genetic and environmental factors. We studied the gene encoding the synaptic… (More)
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Highly Cited
2009
Highly Cited
2009
A number of studies have confirmed that genetic factors play an important role in autism spectrum disorder (ASD). More recently… (More)
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Highly Cited
2007
Highly Cited
2007
SHANK3 (also known as ProSAP2) regulates the structural organization of dendritic spines and is a binding partner of neuroligins… (More)
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Highly Cited
2007
Highly Cited
2007
Mutations in SHANK3, which encodes a synaptic scaffolding protein, have been described in subjects with an autism spectrum… (More)
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Highly Cited
2006
Highly Cited
2006
INTRODUCTION The 22q13.3 deletion syndrome (MIM 606232) is characterised by neonatal hypotonia, normal to accelerated growth… (More)
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