Skip to search formSkip to main contentSkip to account menu

SERPINA3 protein, human

Known as: Cell Growth-Inhibiting Gene 24/25 Protein, Serpin A3, Growth-Inhibiting Protein 24 
Alpha-1-antichymotrypsin (423 aa, ~48 kDa) is encoded by the human SERPINA3 gene. This protein is involved in the inhibition of neutrophil cathepsin… 
National Institutes of Health

Related topics

Related topics

5 relations
Genes, RegulatorRegulation of ProteolysisSERPINA3 gene

Broader (2)

Serpinsalpha 1-Antichymotrypsin

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2020
Review
2020
The effect of cigarette smoking on bronchoalveolar lavage protein profiles from patients with different interstitial lung diseases.
INTRODUCTION The proteomic approach applied to the analysis of BAL gives a panorama of the complex network of proteins of… 
2010
2010
Altered glycosylation profile of purified plasma ACT from Alzheimer’s disease
BackgroundAlzheimer’s disease (AD) is one of the most frequent cause of neurodegenerative disorder in the elderly. Inflammation… 
2005
2005
A new promoter polymorphism in the alpha-1-antichymotrypsin gene is a disease modifier of Alzheimer’s disease
Highly Cited
1998
Highly Cited
1998
Expression of differential immune factors in temporal cortex and cerebellum: The role of α‐1‐antichymotrypsin, apolipoprotein E, and reactive glia in the progression of Alzheimer's disease
A variety of factors and processes have been implicated in the development and progression of the pathology of Alzheimer's… 
1997
1997
Role of the P6-P3' region of the serpin reactive loop in the formation and breakdown of the inhibitory complex.
Serpins have a large external peptide loop known as the reactive loop. Part of the reactive loop functions as the primary… 
1996
1996
Structural investigation of the alpha‐1‐antichymotrypsin: Prostate‐specific antigen complex by comparative model building
Prostate‐specific antigen (PSA), produced by prostate cells, provides an excellent serum marker for prostate cancer. It belongs… 
1994
1994
Interactions of alpha-1-antichymotrypsin, alpha-1-proteinase inhibitor, and alpha-2-macroglobulin with the fungal enzyme, seaprose.
The Semi-alkaline proteinase (Seaprose) from Aspergillus melleus has been tested for its ability to either inactivate or form… 
1992
1992
Alpha-1-antichymotrypsin inhibits the NADPH oxidase-enzyme complex in phorbol ester-stimulated neutrophil membranes.
The generation of superoxide anion and release of granule contents are essential to the bactericidal function of neutrophils, but… 
1992
1992
Detection of a new mutant α‐1‐antichymotrypsin in patients with occlusive‐cerebrovascular disease
Highly Cited
1990
Highly Cited
1990
Clipsin, a chymotrypsin-like protease in rat brain which is irreversibly inhibited by alpha-1-antichymotrypsin.
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)