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SELPLG wt Allele

Known as: PSGL-1, CD162, PSGL1 
Human SELPLG wild-type allele is located in the vicinity of 12q24 and is approximately 12 kb in length. This allele, which encodes P-selectin… 
National Institutes of Health

Related topics

Related topics

7 relations
12q24Cell AdhesionInterleukin Signaling ProcessLigand Binding

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
The role of P- selectin glycoprotein ligand-1 (PSGL-1) in the pathogenesis of obstructive sleep apnea
Obstructive sleep apnoea is characterised by endothelial dysfunction which is associated with enhanced systemic inflammation… 
2014
2014
Delivery of Human EV71 Receptors by Adeno-Associated Virus Increases EV71 Infection-Induced Local Inflammation in Adult Mice
Enterovirus71 (EV71) is now recognized as an emerging neurotropic virus in Asia and one major causative agent of hand-foot-mouth… 
Highly Cited
2009
Highly Cited
2009
Peripheral blood CD4+ T lymphocytes from multiple sclerosis patients are characterized by higher PSGL‐1 expression and transmigration capacity across a human blood‐brain barrier‐derived endothelial…
Mechanisms of T lymphocyte trafficking in the brain remain unclear in MS. We hypothesized that MS is associated with increased… 
2009
2009
Editorial: PSGL‐1—the hidden player in T cell trafficking into the brain in multiple sclerosis?
In MS, a large number of inflammatory cells gain access to the CNS parenchyma, causing inflammation, BBB breakdown, and… 
2008
2008
Molecular characterization of hypoxia-hypothermia-conditioned human endothelial cells and their interaction with human monocytes.
2006
2006
Microparticules circulantes au cours des traumatismes graves et des sepsis : un élément du couplage inflammation–thrombose
2004
2004
P‐selectin glycoprotein ligand 1 therapy ameliorates established collagen‐induced arthritis in DBA/1 mice partly through the suppression of tumour necrosis factor
We investigated the therapeutic potential of P‐selectin glycoprotein ligand (PSGL)‐1 in established collagen‐induced arthritis… 
1998
1998
P-selectin mediates adhesion of the human melanoma cell line NKI-4: identification of glycoprotein ligands.
Activated endothelial cells and stimulated platelets express the cell adhesion molecule P-selectin (CD62P), which mediates… 
1998
1998
Le recrutement des lymphocytes dans les ganglions lymphatiques : apports de la microscopie réalisée in situ sur animal vivant
Continuellement, les lymphocytes circulent du secteur intravasculaire vers les tissus et vice versa afin de rencontrer l'antigene… 
1995
1995
Genomic Organization and Chromosomal Localization of the Gene Encoding Human P-selectin Glycoprotein Ligand (*)
The gene for P-selectin glycoprotein ligand (PSGL-1) has been cloned from a human placenta genomic DNA library. A single intron… 
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