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SELP protein, human

Known as: CD62P Antigen, CD62P protein, human, GMP140 
P-selectin (830 aa, ~91 kDa) is encoded by the human SELP gene. This protein plays a role in leukocyte adhesion to myeloid cells, endothelial cells… 
National Institutes of Health

Related topics

Related topics

17 relations
Alpha GranuleCell AdhesionClusters of differentiationEGF-Like Domain

Broader (1)

P-Selectin

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2012
2012
Activation of caspases‐9, ‐3 and ‐8 in human platelets triggered by BH3‐only mimetic ABT‐737 and calcium ionophore A23187: caspase‐8 is activated via bypass of the death receptors
Platelet apoptosis and activation have been studied in human platelets treated with BH3‐only mimetic ABT‐737 and calcium… 
Highly Cited
2008
Highly Cited
2008
Platelet products prepared by different methods of sedimentation undergo platelet activation differently during storage
BACKGROUND: The activation marker CD40 ligand (CD40L) has recently been demonstrated to be released from the cytoplasm of… 
2002
2002
Inhibition of platelet aggregation and expression of alpha granule membrane protein 140 and thromboxane B2 with pravastatin therapy for hypercholesterolemia.
The drugs in the group of the "statins" lower blood lipids, especially cholesterol, thereby reducing a risk factor for, and… 
2001
2001
Continuous perfusion of pulmonary arteries during total cardiopulmonary bypass favorably affects levels of circulating adhesion molecules and lung function.
OBJECTIVES Lung injury is a serious complication of cardiopulmonary bypass in infants with congenital heart disease and pulmonary… 
Highly Cited
1994
Highly Cited
1994
CD62/P-selectin binding sites for myeloid cells and sulfatides are overlapping.
P-Selectin (CD62/GMP140/PADGEM) is an inducible cell-surface glycoprotein expressed by endothelial cells and platelets following… 
Highly Cited
1993
Highly Cited
1993
Interaction of P-selectin (CD62) and its cellular ligand: analysis of critical residues.
P-Selectin (CD62, PADGEM, GMP140) is a membrane glycoprotein which is rapidly mobilized to the surface of activated platelets and… 
Highly Cited
1992
Highly Cited
1992
Cytoplasmic domain of P-selectin (CD62) contains the signal for sorting into the regulated secretory pathway.
P-selectin (CD62), formerly called GMP-140 or PADGEM, is a membrane protein located in secretory storage granules of platelets… 
Highly Cited
1992
Highly Cited
1992
A monoclonal antibody-based enzyme immunoassay for human GMP-140/P-selectin.
Highly Cited
1991
Highly Cited
1991
Dynamics of leukocyte-platelet adhesion in whole blood
The dynamics of leukocyte-platelet adhesion and platelet-platelet interaction in whole blood are not well understood. Using… 
1991
1991
Downregulation of GMP-140 (CD62 or PADGEM) expression on platelets by N,N-dimethyl and N,N,N-trimethyl derivatives of sphingosine.
GMP-140 (CD62 or PADGEM), a member of the selectin family, is a membrane glycoprotein in secretory granules of platelets and… 
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