SELEX Aptamer Technique

Known as: Aptamer Techniques, SELEX, Technique, SELEX Aptamer, Systematic Evolution of Ligands by Exponential Enrichment 
A method of generating a large library of randomized nucleotides and selecting NUCLEOTIDE APTAMERS by iterative rounds of in vitro selection. A… (More)

Topic mentions per year

Topic mentions per year

1996-2017
05101519962017

Papers overview

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2014
2014
Artificially expanded genetic information systems (AEGISs) are unnatural forms of DNA that increase the number of independently… (More)
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2013
2013
RNA Aptamers refer to RNA oligonulceotides that are capable of binding to specific targets with high affinity and specificity… (More)
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2010
2010
In order to construct an aptasensor, aptamers that show high affinity for target molecules are required. While the systematic… (More)
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2009
2009
Nucleophosmin (NPM) is a multifunctional protein involved in both proliferation and apoptosis. Importantly, NPM negatively… (More)
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2008
2008
Standard systematic evolution of ligands by exponential enrichment (SELEX) protocols require libraries that contain two primers… (More)
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2006
2006
In most cases, anti-protein aptamers are selected by systematic evolution of ligands by exponential enrichment (SELEX) using… (More)
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2003
2003
We developed an integrated method to identify aptamers with only 10 fixed nucleotides through ligation and removal of primer… (More)
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Highly Cited
2002
Highly Cited
2002
The ability to determine the location and relative strength of all transcription-factor binding sites in a genome is important… (More)
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2002
2002
Systematic evolution of ligands by exponential enrichment (SELEX) was used to develop DNA ligands (aptamers) to cholera whole… (More)
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Highly Cited
1996
Highly Cited
1996
The recent development of in vitro methods to select high-affinity ligands by combinatorial chemistry methodologies promises… (More)
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