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SCRIB protein, human

Known as: SCRIB1 protein, human, Scribble, hScrib protein, human 
Protein scribble homolog (1630 aa, ~175 kDa) is encoded by the human SCRIB gene. This protein is involved in cell polarization.
National Institutes of Health

Related topics

Related topics

12 relations
ApoptosisCell ProliferationCellular MembraneIntercellular Junctions

Broader (2)

Membrane ProteinsTumor Suppressor Proteins

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2013
Highly Cited
2013
Regulation of asymmetric cell division and polarity by Scribble is not required for humoral immunity
The production of protective antibody requires effective signalling of naive B cells following encounter with antigen, and the… 
2013
2013
Human T‐cell leukemia virus type 1 Tax protein interacts with and mislocalizes the PDZ domain protein MAGI‐1
Human T‐cell leukemia virus type 1 (HTLV‐1) is the etiological agent of adult T‐cell leukemia (ATL). HTLV‐1 encodes the… 
Highly Cited
2012
Highly Cited
2012
The Scribble/Lgl/Dlg polarity protein complex is a regulator of blood-testis barrier dynamics and spermatid polarity during spermatogenesis.
During spermatogenesis, spermiogenesis that releases sperm into the tubule lumen and restructuring of the blood-testis barrier… 
Highly Cited
2010
Highly Cited
2010
Epithelial and Mesenchymal Cell Biology Tumor Suppressor Scribble Regulates Assembly of Tight Junctions in the Intestinal Epithelium
From the Department of Medicine,* University of Rochester, Rochester, New York; the Department of Pathology and Laboratory… 
Highly Cited
2007
Highly Cited
2007
The PDZ Domain-binding Motif of the Human T Cell Leukemia Virus Type 1 Tax Protein Induces Mislocalization of the Tumor Suppressor hScrib in T cells*
Interactions with cellular PDZ domain-containing proteins obviously contribute to the tumorigenic potential of several viral… 
2007
2007
Human scribble accumulates in colorectal neoplasia in association with an altered distribution of beta-catenin.
Highly Cited
2005
Highly Cited
2005
Localization of PDZ domain containing proteins Discs Large-1 and Scribble in the mouse eye.
PURPOSE In invertebrates such as Drosophila melanogaster and Caenorhabditis elegans, the PDZ domain containing proteins, Discs… 
Review
2005
Review
2005
Epithelial cell polarity genes are required for neural tube closure
Human neural tube defects (NTD) are a heterogeneous group that exhibit complex inheritance, making it difficult to identify the… 
Highly Cited
2004
Highly Cited
2004
A Genetic Screen for Dominant Modifiers of a cyclin E Hypomorphic Mutation Identifies Novel Regulators of S-Phase Entry in Drosophila
Cyclin E together with its kinase partner Cdk2 is a critical regulator of entry into S phase. To identify novel genes that… 
Highly Cited
1988
Highly Cited
1988
Forms of writing and rereading from writing : a preliminary report
In order to describe the developmental patterns of writing and rereading from writing of kindergarten children across group and… 
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