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SCN9A gene

Known as: sodium voltage-gated channel alpha subunit 9, SCN9A, SODIUM CHANNEL, VOLTAGE-GATED, TYPE IX, ALPHA SUBUNIT 
This gene is involved in the perception of pain.
National Institutes of Health

Related topics

Related topics

9 relations
Homo sapiensIonophore activityLigand BindingMolecular Transport

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
α-Cell Dysfunctions and Molecular Alterations in Male Insulinopenic Diabetic Mice Are Not Completely Corrected by Insulin.
Glucagon and α-cell dysfunction are critical in the development of hyperglycemia during diabetes both in humans and rodents. We… 
2015
2015
Novel SCN9A Mutations Underlying Extreme Pain Phenotypes: Unexpected Electrophysiological and Clinical Phenotype Correlations
The importance of NaV1.7 (encoded by SCN9A) in the regulation of pain sensing is exemplified by the heterogeneity of clinical… 
Highly Cited
2013
Highly Cited
2013
Potency optimization of Huwentoxin-IV on hNav 1.7: A neurotoxin TTX-S sodium-channel antagonist from the venom of the Chinese bird-eating spider Selenocosmia huwena
2013
2013
Inherited Pain
Background: Mutations in the sodium channel Nav1.7 cause the inherited pain syndromes IEM and PEPD. Results: The new IEM mutation… 
Highly Cited
2013
Highly Cited
2013
Analysis of the Structural and Molecular Basis of Voltage-sensitive Sodium Channel Inhibition by the Spider Toxin Huwentoxin-IV (μ-TRTX-Hh2a)
Background: The molecular basis for sodium channel inhibition by spider venom peptides is poorly understood. Results: Key toxin… 
2013
2013
A new Nav1.7 mutation in an erythromelalgia patient.
2011
2011
Comparative study of voltage-gated sodium channel α-subunits in non-overlapping four neuronal populations in the rat dorsal root ganglion
2009
2009
Treatment with carbamazepine and gabapentin of a patient with primary erythermalgia (erythromelalgia) identified to have a mutation in the SCN9A gene, encoding a voltage‐gated sodium channel
Primary erythermalgia (erythromelalgia) is a rare autosomal dominant condition characterized by intermittent attacks of erythema… 
2007
2007
Nav1.7, its mutations, and the syndromes that they cause
When many of us went to medical or graduate school, we learned that “the” voltage-dated sodium channel is responsible for… 
2005
2005
Etymological Notes on North-Eastern Neo-Aramaic
∗Akkadian, Kurdish and Syriac words are usually given without reference when they can readily be tracked down in the following… 
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