SCN9A gene

Known as: sodium voltage-gated channel alpha subunit 9, SCN9A, SODIUM CHANNEL, VOLTAGE-GATED, TYPE IX, ALPHA SUBUNIT 
This gene is involved in the perception of pain.
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
The gene SCN9A is responsible for three human pain disorders. Nonsense mutations cause a complete absence of pain, whereas… (More)
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Review
2010
Review
2010
The human sodium channel family includes seven neuronal channels that are essential for the initiation and propagation of action… (More)
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Highly Cited
2010
Highly Cited
2010
Legumes form symbioses with arbuscular mycorrhiza (AM) fungi and nitrogen fixing root nodule bacteria. Intracellular root… (More)
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Highly Cited
2009
Highly Cited
2009
A follow-up study of a large Utah family with significant linkage to chromosome 2q24 led us to identify a new febrile seizure (FS… (More)
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Highly Cited
2007
Highly Cited
2007
The general lack of pain experience is a rare occurrence in humans, and the molecular causes for this phenotype are not well… (More)
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Highly Cited
2006
Highly Cited
2006
The complete inability to sense pain in an otherwise healthy individual is a very rare phenotype. In three consanguineous… (More)
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Highly Cited
2006
Highly Cited
2006
Paroxysmal extreme pain disorder (PEPD), previously known as familial rectal pain (FRP, or OMIM 167400), is an inherited… (More)
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Highly Cited
2004
Highly Cited
2004
Primary erythermalgia is a rare autosomal dominant disease characterised by intermittent burning pain with redness and heat in… (More)
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Highly Cited
2004
Highly Cited
2004
Nine voltage-gated sodium channels are expressed in complex patterns in mammalian nerve and muscle. Three channels, Na(v)1.7, Na… (More)
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Highly Cited
2003
Highly Cited
2003
Ethionamide (ETH) is a structural analog of the antituberculosis drug isoniazid (INH). Both of these drugs target InhA, an enzyme… (More)
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