SCN2A gene

Known as: NAC2, SODIUM CHANNEL, BRAIN TYPE II, ALPHA SUBUNIT, HBSCII 
This gene is involved in neuronal excitation.
National Institutes of Health

Papers overview

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Highly Cited
2013
Highly Cited
2013
OBJECTIVE We aimed to investigate the possible association between SCN2A mutations and early-onset epileptic encephalopathies… (More)
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Highly Cited
2013
Highly Cited
2013
  • 2013
Epileptic encephalopathies are a devastating group of severe childhood epilepsy disorders for which the cause is often unknown… (More)
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Highly Cited
2012
Highly Cited
2012
Multiple studies have confirmed the contribution of rare de novo copy number variations to the risk for autism spectrum disorders… (More)
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Review
2010
Review
2010
The human sodium channel family includes seven neuronal channels that are essential for the initiation and propagation of action… (More)
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Highly Cited
2009
Highly Cited
2009
BACKGROUND Mutations of voltage-gated sodium channel alpha(II) gene, SCN2A, have been described in a wide spectrum of epilepsies… (More)
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Highly Cited
2005
Highly Cited
2005
Sodium channels Na(v)1.2 and Na(v)1.6 are both normally expressed along premyelinated and myelinated axons at different stages of… (More)
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Highly Cited
2004
Highly Cited
2004
Although voltage-gated sodium channels are known to be deployed along experimentally demyelinated axons, the molecular identities… (More)
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Highly Cited
2004
Highly Cited
2004
Mutations, exclusively missense, of voltage-gated sodium channel alpha subunit type 1 (SCN1A) and type 2 (SCN2A) genes were… (More)
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Highly Cited
2003
Highly Cited
2003
Autism is a psychiatric disorder with estimated heritability of 90%. One-third of autistic individuals experience seizures. A… (More)
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Highly Cited
2001
Highly Cited
2001
The GAL879-881QQQ mutation in the cytoplasmic S4-S5 linker of domain 2 of the rat brain IIA sodium channel (Na(v)1.2) results in… (More)
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