Skip to search formSkip to main contentSkip to account menu

SCN2A wt Allele

Known as: NAC2, EIEE11, SCN2A1 
Human SCN2A wild-type allele is located in the vicinity of 2q24.3 and is approximately 153 kb in length. This allele, which encodes sodium channel… 
National Institutes of Health

Related topics

Related topics

8 relations
EPILEPTIC ENCEPHALOPATHY, EARLY INFANTILE, 11Homo sapiensIonophore activityLigand Binding

Broader (1)

SCN2A gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2010
2010
Functional protein expression of multiple sodium channel alpha- and beta-subunit isoforms in neonatal cardiomyocytes.
Highly Cited
2010
Highly Cited
2010
Divergent actions of the pyrethroid insecticides S-bioallethrin, tefluthrin, and deltamethrin on rat Na(v)1.6 sodium channels.
2010
2010
μ-conotoxin KIIIA derivatives with divergent affinities versus efficacies in blocking voltage-gated sodium channels.
The possibility of independently manipulating the affinity and efficacy of pore-blocking ligands of sodium channels is of… 
2010
2010
Sodium Channel Carboxyl-terminal Residue Regulates Fast Inactivation*
The Nav1.2 and Nav1.3 voltage-gated sodium channel isoforms demonstrate distinct differences in their kinetics and voltage… 
Highly Cited
2008
Highly Cited
2008
Specificity, affinity and efficacy of iota-conotoxin RXIA, an agonist of voltage-gated sodium channels Na(V)1.2, 1.6 and 1.7.
Highly Cited
2007
Highly Cited
2007
Regulation of NaV1.2 Channels by Brain-Derived Neurotrophic Factor, TrkB, and Associated Fyn Kinase
Voltage-gated sodium channels are responsible for action potential initiation and propagation in neurons, and modulation of their… 
Highly Cited
2005
Highly Cited
2005
Conjugation of Multiple Copies of Polyethylene Glycol to Hemoglobin Facilitated Through Thiolation: Influence on Hemoglobin Structure and Function
PEGylation induced changes in molecular volume and solution properties of HbA have been implicated as potential modulators of its… 
2004
2004
Benefits of an Insulin Dosage Calculation Device for Adolescents with Type 1 Diabetes Mellitus
OBJECTIVE Multiple daily injection insulin regimens (MDI) and continuous subcutaneous insulin infusion (CSII) allow adolescents… 
Highly Cited
2004
Highly Cited
2004
Identification of binding domains in the sodium channel NaV1.8 intracellular N‐terminal region and annexin II light chain p11
2003
2003
The pentapeptide QYNAD does not block voltage-gated sodium channels
Background: An endogenous pentapeptide (Gln-Tyr-Asn-Ala-Asp; QYNAD) that is present at elevated levels in human CSF from patients… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)