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SCN2A wt Allele
Known as:
NAC2
, EIEE11
, SCN2A1
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Human SCN2A wild-type allele is located in the vicinity of 2q24.3 and is approximately 153 kb in length. This allele, which encodes sodium channel…
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National Institutes of Health
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Related topics
Related topics
8 relations
EPILEPTIC ENCEPHALOPATHY, EARLY INFANTILE, 11
Homo sapiens
Ionophore activity
Ligand Binding
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Broader (1)
SCN2A gene
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2010
2010
Functional protein expression of multiple sodium channel alpha- and beta-subunit isoforms in neonatal cardiomyocytes.
Susann G. Kaufmann
,
R. Westenbroek
,
+6 authors
S. Maier
Journal of Molecular and Cellular Cardiology
2010
Corpus ID: 205809676
Highly Cited
2010
Highly Cited
2010
Divergent actions of the pyrethroid insecticides S-bioallethrin, tefluthrin, and deltamethrin on rat Na(v)1.6 sodium channels.
Jianguo Tan
,
D. Soderlund
Toxicology and Applied Pharmacology
2010
Corpus ID: 205296871
2010
2010
μ-conotoxin KIIIA derivatives with divergent affinities versus efficacies in blocking voltage-gated sodium channels.
Min-min Zhang
,
Tiffany S. Han
,
B. Olivera
,
G. Bulaj
,
D. Yoshikami
Biochemistry
2010
Corpus ID: 20814084
The possibility of independently manipulating the affinity and efficacy of pore-blocking ligands of sodium channels is of…
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2010
2010
Sodium Channel Carboxyl-terminal Residue Regulates Fast Inactivation*
Hai M. Nguyen
,
A. L. Goldin
Journal of Biological Chemistry
2010
Corpus ID: 17307541
The Nav1.2 and Nav1.3 voltage-gated sodium channel isoforms demonstrate distinct differences in their kinetics and voltage…
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Highly Cited
2008
Highly Cited
2008
Specificity, affinity and efficacy of iota-conotoxin RXIA, an agonist of voltage-gated sodium channels Na(V)1.2, 1.6 and 1.7.
B. Fiedler
,
Min-min Zhang
,
+5 authors
D. Yoshikami
Biochemical Pharmacology
2008
Corpus ID: 34241277
Highly Cited
2007
Highly Cited
2007
Regulation of NaV1.2 Channels by Brain-Derived Neurotrophic Factor, TrkB, and Associated Fyn Kinase
M. Ahn
,
D. Beacham
,
R. Westenbroek
,
T. Scheuer
,
W. Catterall
Journal of Neuroscience
2007
Corpus ID: 16257170
Voltage-gated sodium channels are responsible for action potential initiation and propagation in neurons, and modulation of their…
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Highly Cited
2005
Highly Cited
2005
Conjugation of Multiple Copies of Polyethylene Glycol to Hemoglobin Facilitated Through Thiolation: Influence on Hemoglobin Structure and Function
B. Manjula
,
A. Tsai
,
+7 authors
S. Acharya
The Protein Journal
2005
Corpus ID: 35397375
PEGylation induced changes in molecular volume and solution properties of HbA have been implicated as potential modulators of its…
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2004
2004
Benefits of an Insulin Dosage Calculation Device for Adolescents with Type 1 Diabetes Mellitus
Nicole S Glaser
,
S.B. Iden,
,
+4 authors
B. Goodlin-Jones,
Journal of Pediatric Endocrinology & Metabolism…
2004
Corpus ID: 31809626
OBJECTIVE Multiple daily injection insulin regimens (MDI) and continuous subcutaneous insulin infusion (CSII) allow adolescents…
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Highly Cited
2004
Highly Cited
2004
Identification of binding domains in the sodium channel NaV1.8 intracellular N‐terminal region and annexin II light chain p11
W. Poon
,
M. Malik-Hall
,
J. Wood
,
K. Okuse
FEBS Letters
2004
Corpus ID: 30351708
2003
2003
The pentapeptide QYNAD does not block voltage-gated sodium channels
Theodore R. Cummins
,
M. Renganathan
,
+5 authors
S. G. Waxman
Neurology
2003
Corpus ID: 11168082
Background: An endogenous pentapeptide (Gln-Tyr-Asn-Ala-Asp; QYNAD) that is present at elevated levels in human CSF from patients…
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