SCH 351125

Known as: SCH-351125, SCH351125 
 

Topic mentions per year

Topic mentions per year

2001-2012
02420012012

Papers overview

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2010
2010
OBJECTIVE C-C chemokine receptor type 5 (CCR5), a chemokine receptor expressed on T cells and macrophages, and its ligands are… (More)
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Highly Cited
2006
Highly Cited
2006
The CC-chemokine receptor 5 (CCR5) is the major coreceptor for macrophage-tropic (R5) HIV-1 strains. Several small molecule… (More)
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Highly Cited
2005
Highly Cited
2005
4-{[4-({(3R)-1-Butyl-3-[(R)-cyclohexyl(hydroxy)methyl]-2,5dioxo-1,4,9-triazaspiro[5.5]undec-9-yl}methyl)phenyl]oxy}benzoic acid… (More)
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2005
2005
The identification and relative contribution of human cytochrome P450 enzyme(s) involved in the metabolism of SCH 351125 were… (More)
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Highly Cited
2003
Highly Cited
2003
Human immunodeficiency virus type 1 (HIV-1) entry is mediated by the consecutive interaction of the envelope glycoprotein gp120… (More)
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2003
2003
The small-molecule CCR5 antagonist SCH-C (SCH 351125) was tested for its ability to inhibit HIV-1 replication in peripheral blood… (More)
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2003
2003
The separation and biological evaluation of rotamers as well as interconversion studies on rotamers of our clinical candidate SCH… (More)
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2002
2002
SCH-C (SCH 351125) is a small-molecule antagonist of the human immunodeficiency virus type 1(HIV-1) coreceptor CCR5. It has in… (More)
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2001
2001
We describe here the identification and properties of SCH-C (SCH 351125), a small molecule inhibitor of HIV-1 entry via the CCR5… (More)
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2001
2001
Structure-activity studies on piperidino-piperidine 3 led to the discovery of SCH 351125 (1), a selective CCR5 antagonist with… (More)
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