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Ancriviroc
Known as:
SCH-C
A C-C Chemokine Receptor Type 5 (CCR5) antagonist with activity against the human immunodeficiency virus, HIV-1. Ancriviroc is an orally bioavailable…
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National Institutes of Health
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SCH 351125
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Highly Cited
2004
Highly Cited
2004
Spirodiketopiperazine-Based CCR5 Inhibitor Which Preserves CC-Chemokine/CCR5 Interactions and Exerts Potent Activity against R5 Human Immunodeficiency Virus Type 1 In Vitro
K. Maeda
,
H. Nakata
,
+9 authors
H. Mitsuya
Journal of Virology
2004
Corpus ID: 5564802
ABSTRACT We identified a novel spirodiketopiperazine (SDP) derivative, AK602/ONO4128/GW873140, which specifically blocked the…
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Review
2003
Review
2003
Specific CD4 down‐modulating compounds with potent anti‐HIV activity
K. Vermeire
,
D. Schols
Journal of Leukocyte Biology
2003
Corpus ID: 23700417
Despite the availability of the current clinically approved anti‐HIV drugs, new classes of effective antiviral agents are still…
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Highly Cited
2001
Highly Cited
2001
SCH-C (SCH 351125), an orally bioavailable, small molecule antagonist of the chemokine receptor CCR5, is a potent inhibitor of HIV-1 infection in vitro and in vivo
J. Strizki
,
Serena Xu
,
+22 authors
B. Baroudy
Proceedings of the National Academy of Sciences…
2001
Corpus ID: 256474
We describe here the identification and properties of SCH-C (SCH 351125), a small molecule inhibitor of HIV-1 entry via the CCR5…
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