Skip to search formSkip to main contentSkip to account menu

S-Methyl-5'-Thioadenosine Phosphorylase

Known as: MTAPase, MeSAdo Phosphorylase, 5'-Methylthioadenosine Phosphorylase 
S-methyl-5'-thioadenosine phosphorylase (283 aa, ~31 kDa) is encoded by the human MTAP gene. This protein plays a role in amino acid, nucleotide and… 
National Institutes of Health

Related topics

Related topics

9 relations
5'-Methylthioadenosine phosphorylaseAmino Acid BiosynthesisCarbohydrate MetabolismCytoplasmic matrix

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2012
2012
Increasing the therapeutic index of 5-fluorouracil and 6-thioguanine by targeting loss of MTAP in tumor cells
Methylthioadenosine phosphorylase (MTAP), a key enzyme in the catabolism of 5′-deoxy-5′-methylthioadenosine (MTA), catalyzes the… 
2009
2009
Dual Function Microtubule- and Mitochondria-Associated Proteins Mediate Mitotic Cell Death
Background: Survival and evolution of aneuploid cells after an asymmetric segregation of chromosomes at mitosis may be the common… 
2009
2009
Genome‐wide associations studies for melanoma and nevi
Two new genome wide association studies (GWAS) add to our understanding of genetic risk factors for development of melanoma and… 
2006
2006
Tissue microarray analysis of methylthioadenosine phosphorylase protein expression in melanocytic skin tumors.
BACKGROUND Using tissue microarrays, we investigated whether methylthioadenosine phosphorylase (MTAP) protein expression is… 
2004
2004
Structural comparison of MTA phosphorylase and MTA/AdoHcy nucleosidase explains substrate preferences and identifies regions exploitable for inhibitor design.
The development of new and effective antiprotozoal drugs has been a difficult challenge because of the close similarity of the… 
2003
2003
Identification of gene expression profiles predicting tumor cell response to L-alanosine.
Review
1998
Review
1998
Codeletion of CDKN2 and MTAP genes in a subset of non‐Hodgkin's lymphoma may be associated with histologic transformation from low‐grade to diffuse large‐cell lymphoma
Identifying the various genetic alterations that contribute to lymphomagenesis is key to our improved understanding of the… 
Highly Cited
1995
Highly Cited
1995
Refined mapping of genomic rearrangements involving the short arm of chromosome 9 in acute lymphoblastic leukemias and other hematologic malignancies.
Deletions of chromosomal band 9p21 have been detected in various tumor types as well as in more than 20% of acute lymphoblastic… 
Highly Cited
1992
Highly Cited
1992
Mapping of the shortest region of overlap of deletions of the short arm of chromosome 9 associated with human neoplasia.
1988
1988
Substrate specificities of 5'-deoxy-5'-methylthioadenosine phosphorylase from Trypanosoma brucei brucei and mammalian cells.
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)