S-Methyl-5'-Thioadenosine Phosphorylase

Known as: MTAPase, MeSAdo Phosphorylase, 5'-Methylthioadenosine Phosphorylase 
S-methyl-5'-thioadenosine phosphorylase (283 aa, ~31 kDa) is encoded by the human MTAP gene. This protein plays a role in amino acid, nucleotide and… (More)
National Institutes of Health

Papers overview

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Highly Cited
2016
Highly Cited
2016
The discovery of cancer dependencies has the potential to inform therapeutic strategies and to identify putative drug targets… (More)
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Highly Cited
2016
Highly Cited
2016
5-Methylthioadenosine phosphorylase (MTAP) is a key enzyme in the methionine salvage pathway. The MTAP gene is frequently deleted… (More)
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2012
2012
BACKGROUND Advantages offered by canine population substructure, combined with clinical presentations similar to human disorders… (More)
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2011
2011
We performed a genome-wide association study of melanoma in a discovery cohort of 2,168 Australian individuals with melanoma and… (More)
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Highly Cited
2010
Highly Cited
2010
OBJECTIVE We tested the hypothesis that expression of transcripts adjacent to the chromosome 9p21 (Chr9p21) locus of coronary… (More)
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Highly Cited
2009
Highly Cited
2009
BACKGROUND Genome-wide association studies (GWAS) have linked common single nucleotide polymorphisms (SNPs) on chromosome 9p21… (More)
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Highly Cited
2009
Highly Cited
2009
A high melanocytic nevi count is the strongest known risk factor for cutaneous melanoma. We conducted a genome-wide association… (More)
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Highly Cited
2003
Highly Cited
2003
PURPOSE Homozygous deletions at chromosome region 9p21 targeting the CDKN2A gene have been reported as a common cytogenetic… (More)
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Highly Cited
2002
Highly Cited
2002
The human methylthioadenosine phosphorylase (MTAP) gene is located on 9p21 and is frequently homozygously deleted, along with p16… (More)
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1992
1992
Previous studies have suggested that structural abnormalities involving the short arm of chromosome 9 are frequently associated… (More)
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