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S-Adenosylmethionine

Known as: S-(5'-Deoxyadenosin-5'-yl)-L-methionine, SAMe, 5'-[(3-Amino-3-carboxypropyl)methylsulfonio]-5'-deoxyadenosine Hydroxide, Inner Salt 
A nutritional supplement that is synthesized from adenosine triphosphate (ATP) and the amino acid methionine by the endogenous essential enzyme… Expand
National Institutes of Health

Related topics

Related topics

23 relations

Broader (4)

AdenosineAmino Acids, SulfurMethioninehigh energy compound

Narrower (9)

AdoEnYnFO-1561GumbaralS Amet
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In BloodMAT1A geneNCIt Antineoplastic Agent Terminologyagonists
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Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2006
Highly Cited
2006
Convergence Culture: Where Old and New Media Collide
"Convergence Culture" maps a new territory: where old and new media intersect, where grassroots and corporate media collide… Expand
Review
2004
Review
2004
S-adenosylmethionine: nothing goes to waste.
S-adenosylmethionine (SAM or AdoMet) is a biological sulfonium compound known as the major biological methyl donor in reactions… Expand
Review
2002
Review
2002
SAM (dependent) I AM: the S-adenosylmethionine-dependent methyltransferase fold.
The S-adenosylmethionine-dependent methyltransferase enzymes share little sequence identity, but incorporate a highly conserved… Expand
Review
2002
Review
2002
S‐Adenosylmethionine: a control switch that regulates liver function
Genome sequence analysis reveals that all organisms synthesize S‐adenosylmethionine (AdoMet) and that a large fraction of all… Expand
Review
2001
Review
2001
A Survey of Structure−Property Relationships of Surfaces that Resist the Adsorption of Protein
This paper describes the use of surface plasmon resonance (SPR) spectroscopy and self-assembled monolayers (SAMs) to determine… Expand
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Highly Cited
2000
Highly Cited
2000
LDL cholesterol upregulates synthesis of asymmetrical dimethylarginine in human endothelial cells: involvement of S-adenosylmethionine-dependent methyltransferases.
Asymmetrical dimethylarginine (ADMA) is an endogenous nitric oxide synthase inhibitor. It is formed by protein arginine N… Expand
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Highly Cited
1998
Highly Cited
1998
Alkanethiolate Gold Cluster Molecules with Core Diameters from 1.5 to 5.2 nm: Core and Monolayer Properties as a Function of Core Size
The mean size of the gold (Au) core in the synthesis of dodecanethiolate-stabilized Au cluster compounds can be finely adjusted… Expand
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Review
1997
Review
1997
S-adenosylmethionine synthesis: molecular mechanisms and clinical implications.
Methionine adenosyltransferase (MAT) is an ubiquitous enzyme that catalyzes the synthesis of S-adenosylmethionine from methionine… Expand
Review
1992
Review
1992
The pathogenesis of homocysteinemia: interruption of the coordinate regulation by S-adenosylmethionine of the remethylation and transsulfuration of homocysteine.
A unified, biochemical hypothesis is proposed to explain the pathogenesis of homocysteinemia. This hypothesis is based on the… Expand
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Highly Cited
1990
Highly Cited
1990
Methionine metabolism in mammals.
  • J. Finkelstein
  • The Journal of nutritional biochemistry
  • 1990
    • Corpus ID: 32264340
Article de synthese sur le metabolisme de la methionine, acide amine essentiel, chez les mammiferes. Etude du schema metabolique… Expand
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