S-Adenosylmethionine

Known as: S-(5'-Deoxyadenosin-5'-yl)-L-methionine, SAMe, 5'-[(3-Amino-3-carboxypropyl)methylsulfonio]-5'-deoxyadenosine Hydroxide, Inner Salt 
A nutritional supplement that is synthesized from adenosine triphosphate (ATP) and the amino acid methionine by the endogenous essential enzyme… (More)
National Institutes of Health

Papers overview

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Review
2014
Review
2014
ing a H-atom from substrate. These and other kinetics studies demonstrated that PFL-AE could undergo multiple turnover events… (More)
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Highly Cited
2013
Highly Cited
2013
Threonine is the only amino acid critically required for the pluripotency of mouse embryonic stem cells (mESCs), but the detailed… (More)
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Highly Cited
2004
Highly Cited
2004
BACKGROUND Autism is a complex neurodevelopmental disorder that usually presents in early childhood and that is thought to be… (More)
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Review
2002
Review
2002
The S-adenosylmethionine-dependent methyltransferase enzymes share little sequence identity, but incorporate a highly conserved… (More)
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Highly Cited
2000
Highly Cited
2000
Asymmetrical dimethylarginine (ADMA) is an endogenous nitric oxide synthase inhibitor. It is formed by protein arginine N… (More)
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Review
1997
Review
1997
Methionine adenosyltransferase (MAT) is an ubiquitous enzyme that catalyzes the synthesis of S-adenosylmethionine from methionine… (More)
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Review
1996
Review
1996
S-Adenosylmethionine (AdoMet or SAM) plays a pivotal role as a methyl donor in a myriad of biological and biochemical events… (More)
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Highly Cited
1996
Highly Cited
1996
S-Adenosylmethionine is an essential ubiquitous metabolite central to many biochemical pathways, including transmethylation and… (More)
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Highly Cited
1994
Highly Cited
1994
Three regions of sequence similarity have been reported in several protein and small-molecule S-adenosylmethionine-dependent… (More)
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Review
1992
Review
1992
A unified, biochemical hypothesis is proposed to explain the pathogenesis of homocysteinemia. This hypothesis is based on the… (More)
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