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S-(3-hydroxypropyl)cysteine N-acetate

Known as: N-acetyl-S-(3-hydroxypropyl)cysteine, 3-Hydroxypropylmercapturic Acid, 1-(N-Acetylcysteinyl)-Propan-3-Ol 
A modified form of acetylcysteine that is a metabolite of acrolein and may be found in the urine of smokers.
National Institutes of Health

Papers overview

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Highly Cited
2015
Highly Cited
2015
INTRODUCTION Electronic cigarettes (e-cigarettes) are rapidly increasing in popularity but little information is available on… Expand
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Highly Cited
2012
Highly Cited
2012
Reduction-sensitive reversibly core-cross-linked micelles were developed based on poly(ethylene glycol)-b-poly(N-2-hydroxypropyl… Expand
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Highly Cited
2009
Highly Cited
2009
Phase I studies of [N-(2-hydroxypropyl)methacrylamide] (HPMA) copolymer-doxorubicin previously showed signs of activity coupled… Expand
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Review
2009
Review
2009
  • Ruth Duncan
  • Advanced drug delivery reviews
  • 2009
  • Corpus ID: 38517927
The concept of polymer-drug conjugates was proposed more than 30 years ago, and an N-(2-hydroxypropyl)methacrylamide (HPMA… Expand
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Highly Cited
2004
Highly Cited
2004
Angiogenesis is crucial for tumor growth. Angiogenesis inhibitors, such as O-(chloracetyl-carbamoyl) fumagillol (TNP-470), are… Expand
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Highly Cited
2004
Highly Cited
2004
OBJECTIVES Substances such as monomers may be released from composite resin systems and may induce adverse effects in biological… Expand
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Highly Cited
2002
Highly Cited
2002
AbstractPurpose. Overexpression of hyaluronan (HA) receptors on cancer cells results in enhanced endocytotic uptake of the drug… Expand
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Highly Cited
2001
Highly Cited
2001
In this paper we describe the synthesis, physico-chemical characteristics and results of tests of biological activity of polymer… Expand
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Highly Cited
1995
Highly Cited
1995
The molecular weight-dependence of tumour capture of N-(2-hydroxypropyl)methacrylamide (HPMA) copolymers (fractions of mw 22,000… Expand
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Highly Cited
1987
Highly Cited
1987
A copolymer of N-(2-hydroxypropyl) methacrylamide (HPMA) and N-methacryloyltyrosinamide was prepared and fractionated using… Expand
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