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Roflumilast

Known as: 3-Cyclopropylmethoxy-N-(3,5-dichloropyridin-4-yl)-4-(difluoromethoxy)benzamide, 3-cyclopropylmethoxy-4-difluoromethoxy-N-(3,5-di-chloropyrid-4-yl)benzamide, ROF 
An orally available, long-acting inhibitor of phosphodiesterase (PDE) type 4 (PDE4), with anti-inflammatory and potential antineoplastic activities… 
National Institutes of Health

Related topics

Related topics

5 relations

Broader (3)

AminopyridinesBenzamidesCyclopropanes

Narrower (1)

Daliresp
NCIt Antineoplastic Agent Terminology

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
Roflumilast partially reverses smoke-induced mucociliary dysfunction
BackgroundPhosphodiesterases (PDEs) break down cAMP, thereby regulating intracellular cAMP concentrations and diffusion. Since… 
Highly Cited
2013
Highly Cited
2013
EM-TV Methods for Inverse Problems with Poisson Noise
We address the task of reconstructing images corrupted by Poisson noise, which is important in various applications such as… 
Highly Cited
2011
Highly Cited
2011
A Novel Lightwave Centralized Bidirectional Hybrid Access Network: Seamless Integration of RoF With WDM-OFDM-PON
We experimentally demonstrated a novel lightwave centralized hybrid bidirectional access network for integration of wavelength… 
Review
2008
Review
2008
Next Generation PON in Emerging Networks
  • R. Lin
  • OFC/NFOEC - Conference on Optical Fiber…
  • 2008
  • Corpus ID: 10113223
This paper presents an overview on the next generation PON techniques in which the developing trends of 10 G EPON, WDM-PON… 
Highly Cited
2008
Highly Cited
2008
Optical direct-detection OFDM signal generation for radio-over-fiber link using frequency doubling scheme with carrier suppression.
This investigation demonstrates the generation of OFDM-RoF signal using frequency doubling technique for the first time, to the… 
Highly Cited
2007
Highly Cited
2007
Electrooptic Polymer Ring Resonator Modulation up to 165 GHz
Modulation is demonstrated at 84, 111, 139, and 165 GHz resonances of a traveling-wave electrooptic polymer ring-resonator-based… 
Highly Cited
2007
Highly Cited
2007
A Novel Radio-Over-Fiber System With Wavelength Reuse for Upstream Data Connection
We have experimentally demonstrated a novel wavelength reuse scheme for up-link connection in a radio-over-fiber (ROF) system… 
Highly Cited
2006
Highly Cited
2006
A phosphodiesterase 4 inhibitor inhibits matrix protein deposition in airways in vitro.
Highly Cited
2005
Highly Cited
2005
Characterizations of supercontinuum light source for WDM millimeter-wave-band radio-on-fiber systems
We qualitatively evaluate for the first time phase-noise characteristics of radio-frequency carriers of a supercontinuum… 
Highly Cited
2004
Highly Cited
2004
PER and EVM measurements of a radio-over-fiber network for cellular and WLAN system applications
This paper investigates the transmission characteristics of an optical signal that is modulated by a radio-frequency signal using… 
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