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Ritanserin

Known as: 5H-Thiazolo(3,2-a)pyrimidin-5-one, 6-(2-(4-(bis(4-fluorophenyl)methylene)-1-piperidinyl)ethyl)-7-methyl-, Ritanserin [Chemical/Ingredient], 6-(2-(4-(Bis(P-Fluorophenyl)Methylene)-Piperidino)Ethyl)-7-Methyl-5h-Thiazolo-(3,2-A)Pyrimidin-5-One 
A selective and potent serotonin-2 antagonist that is effective in the treatment of a variety of syndromes related to anxiety and depression. The… 
National Institutes of Health

Related topics

Related topics

14 relations

Broader (6)

Anti-Anxiety AgentsAntidepressive Agents, Second-GenerationAntipsychotic AgentsPyrimidinones
In Bloodagonistsanalogs & derivativesantagonists & inhibitors

Narrower (1)

R-55667

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
1999
Highly Cited
1999
Effects of antipsychotic drugs on extracellular dopamine levels in rat medial prefrontal cortex and nucleus accumbens.
The present study was designed to compare the effects of typical and atypical antipsychotic drugs on extracellular dopamine (DA… 
Highly Cited
1999
Highly Cited
1999
Selective blockade of serotonin-2C/2B receptors enhances mesolimbic and mesostriatal dopaminergic function: a combined in vivo electrophysiological and microdialysis study
Highly Cited
1997
Highly Cited
1997
Risk Assessment Behaviour: Evaluation of Utility in the Study of 5-HT-Related Drugs in the Rat Elevated Plus-Maze Test
Highly Cited
1993
Highly Cited
1993
Shock-induced ultrasonic vocalization in young adult rats: a model for testing putative anti-anxiety drugs.
Highly Cited
1989
Highly Cited
1989
Effects of serotonergic agonists and antagonists on corticotropin-releasing hormone secretion by explanted rat hypothalami
Highly Cited
1989
Highly Cited
1989
Anxiogenic-like effects of mCPP and TFMPP in animal models are opposed by 5-HT1C receptor antagonists.
Highly Cited
1987
Highly Cited
1987
Stimulation of corticosterone and beta-endorphin secretion in the rat by selective 5-HT receptor subtype activation.
Highly Cited
1987
Highly Cited
1987
Two distinct effects of 5-hydroxytryptamine on single cortical neurons
Highly Cited
1986
Highly Cited
1986
5-Hydroxytryptamine-2 antagonist increases human slow wave sleep
Highly Cited
1985
Highly Cited
1985
The pharmacology of the hypothermic response in mice to 8-hydroxy-2-(DI-n-propylamino)tetralin (8-OH-DPAT) A model of presynaptic 5-HT1 function
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