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Ripasudil

National Institutes of Health

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K-115

Papers overview

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2020
2020
Oxytocin induced epithelium-mesenchimal transition through Rho-ROCK pathway in ARPE-19 cells, a human retinal pigmental cell line.
2020
2020
Computational systematic selectivity of the Fasalog inhibitors between ROCK-I and ROCK-II kinase isoforms in Alzheimer's disease
2019
2019
Safety and Efficacy of Ripasudil in Japanese Patients with Glaucoma or Ocular Hypertension: 3-month Interim Analysis of ROCK-J, a Post-Marketing Surveillance Study
IntroductionTo evaluate the safety and intraocular pressure (IOP)-lowering effects of a ripasudil 0.4% ophthalmic solution in… 
2019
2019
Protection of ripasudil, a Rho kinase inhibitor, in lipopolysaccharides-induced acute pneumonia in mice.
Pneumonia is a major cause of morbidity and mortality of infectious diseases, especially in children. Ripasudil (K-115), a… 
2019
2019
Changes in corneal endothelial cell shape after treatment with one drop of ROCK inhibitor
Purpose We performed an investigation of the temporal impact on corneal endothelial cell (CEC) shape after ophthalmic… 
Review
2019
Review
2019
New Insights Into Corneal Endothelial Regeneration
Purpose of ReviewThis article reviews our current understanding of the regenerative capacity of the corneal endothelium and… 
2019
2019
Correction to: Safety and Efficacy of Ripasudil in Japanese Patients with Glaucoma or Ocular Hypertension: 3-month Interim Analysis of ROCK-J, a Post-Marketing Surveillance Study
In the original publication values in the results section are incorrect. Errors were also identified in Fig. 5 
2018
2018
Effectiveness and safety of switching from prostaglandin analog monotherapy to prostaglandin/timolol fixed combination therapy or adding ripasudil
PurposeTo compare the effectiveness and safety of either switching from topical prostaglandin (PG) analog monotherapy to topical… 
2018
2018
Effects of ripasudil, a ROCK inhibitor, on retinal edema and nonperfusion area in a retinal vein occlusion murine model.
2017
2017
The Future of Glaucoma Treatment Ripasudil
Glaucoma is a leading cause for worldwide blindness and is characterized by progressive optic nerve damage. The etiology of… 
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