Shinsuke Nakamura

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PURPOSE To clarify the effects on the visual pathway that occur following retinal damage, we examined the morphological alterations present in the superior colliculus (SC) after N-methyl-D-aspartate (NMDA)-induced retinal damage in mice. METHODS NMDA was injected into the vitreous body of the left eye in mice to induce retinal damage. The time-dependent(More)
This paper proposes a method for controlling an object with parallel surfaces in a horizontal plane by a pair of finger robots. The control method can achieve stable grasping, relative orientation control, and relative position control of the grasped object. The control inputs require neither any object parameters nor any object sensing, such as tactile(More)
The mouse model of oxygen-induced retinopathy (OIR) has been widely used for studies of retinopathy of prematurity (ROP). This disorder, characterized by abnormal vascularization of the retina, tends to occur in low birth weight neonates after exposure to high supplemental oxygen. Currently, the incidence of ROP is increasing because of increased survival(More)
Endoplasmic reticulum (ER) stress occurs as a result of accumulation of unfolded or misfolded proteins in the ER and is involved in the mechanisms of various diseases, such as cancer and neurodegeneration. The goal of the present study was to clarify the relationship between ER stress and pathological neovascularization in the retina. Proliferation and(More)
PURPOSE This study aimed to characterize the functional and morphologic changes in a murine model of ocular ischemic disease caused by vascular occlusion. METHODS Retinal ischemia was induced by unilateral ligation of the pterygopalatine artery (PPA) and the external carotid artery (ECA) in anesthetized mice. Changes in ocular blood flow and retinal(More)
This paper proposes stable grasping and angle control methods of an object with parallel surfaces by a pair of finger robots in a horizontal plane. The method does not require any object sensing for stable grasping but only measurement of the object angle for absolute orientation angle control. Relative orientation angle control of the grasped object can be(More)
The purpose of this study was to determine whether lomerizine, a Ca(2+) channel blocker, protects against neuronal degeneration within the dorsal lateral geniculate nucleus (dLGN) and superior colliculus (SC) after the induction of retinal damage by intravitreal injection of N-methyl-D-aspartate (NMDA) in mice. NMDA (20 mM/2 microL) was injected into the(More)
Realistic drape and motion of virtual clothing is now possible by using an up-to-date cloth simulator, but it is even difficult and time consuming to adjust and tune many parameters to achieve an authentic looking of a real particular fabric. Bhat et al. [2003] proposed a way to estimate the parameters from the video data of real fabrics. However, this(More)
PURPOSE Inflammatory response has a critical role in neuronal damage after retinal ischemia-reperfusion (I/R) injury, and is regulated tightly by the toll-like receptor (TLR) 4. This study aimed to determine whether TLR4 is involved with injury in an ocular ischemic syndrome mice model and to clarify the downstream pathway of TLR4. METHODS To cause(More)
The purpose of this study, on mice, was to determine whether memantine, a glutamate-receptor antagonist of the N-methyl-(d)-aspartate (NMDA) subtype, protects against neuronal degeneration in the dorsal lateral geniculate nucleus (dLGN) and superior colliculus (SC) after the induction of retinal damage by intravitreal injection of NMDA. NMDA (20 mM/2(More)