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Ribonucleoside-diphosphate reductase

Known as: Ribonucleoside Diphosphate Reductase, Reductase, Ribonucleoside Diphosphate, Diphosphate Reductase, Ribonucleoside 
An enzyme of the oxidoreductase class that catalyzes the formation of 2'-deoxyribonucleotides from the corresponding ribonucleotides using NADPH as… Expand
National Institutes of Health

Papers overview

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Highly Cited
2011
Highly Cited
2011
An enzyme that removes supercoils from DNA can cause mutations when RNA bases accidentally get incorporated into the DNA. The… Expand
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Highly Cited
2007
Highly Cited
2007
ABSTRACT The 90S preribosomal particle is required for the production of the 18S rRNA from a pre-rRNA precursor. Despite the… Expand
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Highly Cited
2003
Highly Cited
2003
Synthetic analogs of the 5'-terminal caps of eukaryotic mRNAs and snRNAs are used in elucidating such physiological processes as… Expand
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Highly Cited
2002
Highly Cited
2002
ABSTRACT We report here the results of a systematic high-resolution X-ray crystallographic analysis of complexes of the hepatitis… Expand
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Highly Cited
1991
Highly Cited
1991
It has been found that 2'-deoxy-2'-methyleneuridine (MdUrd), 2'-deoxy-2'-methylenecytidine (MdCyd), and 2'-deoxy-2',2… Expand
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Highly Cited
1990
Highly Cited
1990
The new deoxycytidine analogue 2',2'-difluorodeoxycytidine (dFdC) is a specific inhibitor of DNA synthesis that has marked… Expand
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Highly Cited
1990
Highly Cited
1990
We have demonstrated that when the covalently joined ends of linear adeno-associated virus (AAV) DNA are resolved in vitro, the… Expand
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Highly Cited
1979
Highly Cited
1979
Purified calf thymus ribonucleoside-diphosphate reductase (2'-deoxyribonucleoside-diphosphate:oxidized-thioredoxin 2… Expand
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Highly Cited
1969
Highly Cited
1969
Abstract The allosteric effectors, ATP, dATP, dGTP and dTTP, regulate both the level of activity and the substrate specificity of… Expand
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Highly Cited
1968
Highly Cited
1968
Hydroxyurea, a compound which inhibits the growth of rapidly proliferating tissues in animals and man, is known to inhibit DNA… Expand
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