Ribonucleoside-diphosphate reductase

Known as: Ribonucleoside Diphosphate Reductase, Reductase, Ribonucleoside Diphosphate, Diphosphate Reductase, Ribonucleoside 
An enzyme of the oxidoreductase class that catalyzes the formation of 2'-deoxyribonucleotides from the corresponding ribonucleotides using NADPH as… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1957-2018
05101519572017

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11 relations
In BloodProcess of secretionantagonists & inhibitorsaspects of radiation effects
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Narrower (3)

NrdI protein, Mycoplasma gallisepticumRnr4 protein, S cerevisiaeribonucleotide reductase M2

Broader (1)

Ribonucleotide Reductase

Related mentions per year

Related mentions per year

1936-2019
19401960198020002020
Ribonucleoside-diphosphate reductase
standards characteristics
physiological aspects
Ribonucleotide Reductase
chemical synthesis
ribonucleotide reductase M2

Papers overview

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Highly Cited
2011
Highly Cited
2011
Mutagenic processing of ribonucleotides in DNA by yeast topoisomerase I.
The ribonuclease (RNase) H class of enzymes degrades the RNA component of RNA:DNA hybrids and is important in nucleic acid… (More)
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2007
2007
Defective ribonucleoside diphosphate reductase impairs replication fork progression in Escherichia coli.
The observed lengthening of the C period in the presence of a defective ribonucleoside diphosphate reductase has been assumed to… (More)
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Highly Cited
2002
Highly Cited
2002
Structural analysis of the hepatitis C virus RNA polymerase in complex with ribonucleotides.
We report here the results of a systematic high-resolution X-ray crystallographic analysis of complexes of the hepatitis C virus… (More)
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Highly Cited
1990
Highly Cited
1990
Inhibition of ribonucleotide reduction in CCRF-CEM cells by 2',2'-difluorodeoxycytidine.
The new deoxycytidine analogue 2',2'-difluorodeoxycytidine (dFdC) is a specific inhibitor of DNA synthesis that has marked… (More)
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1984
1984
Primary structure of the Escherichia coli ribonucleoside diphosphate reductase operon.
The nucleotide sequence of the Escherichia coli K-12 DNA comprising the operon for the structural genes of the subunits of… (More)
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1983
1983
Regulation of ribonucleoside diphosphate reductase mRNA synthesis in Escherichia coli.
A RNA-DNA hybridization assay for ribonucleoside diphosphate reductase (RDP reductase) mRNA was used to determine whether control… (More)
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1983
1983
Characterization of the mRNA coding for ribonucleoside diphosphate reductase in Escherichia coli.
Total Escherichia coli RNA was separated by electrophoresis on methyl mercury agarose gels, transferred to diazobenzyloxymethyl… (More)
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1979
1979
Glutathione-dependent hydrogen donor system for calf thymus ribonucleoside-diphosphate reductase.
Purified calf thymus ribonucleoside-diphosphate reductase (2'-deoxyribonucleoside-diphosphate:oxidized-thioredoxin 2… (More)
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1973
1973
Physicochemical characterization of ribonucleoside diphosphate reductase from Escherichia coli.
Ribonucleotide reductase from Escherichia coli consists of two nonidentical subunits, proteins Bl and B2. Affinity chromatography… (More)
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Highly Cited
1968
Highly Cited
1968
Inhibition of ribonucleoside diphosphate reductase by hydroxyurea.
 
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