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Rhodamine 123

Known as: Rhodamine 123 [Chemical/Ingredient], Xanthylium, 3,6-diamino-9-(2-(methoxycarbonyl)phenyl)-, chloride 
A fluorescent probe with low toxicity which is a potent substrate for P-glycoprotein and the bacterial multidrug efflux transporter. It is used to… 
National Institutes of Health

Related topics

Related topics

10 relations

Broader (1)

Fluorescent Dyes
In BloodP-GlycoproteinP-Glycoproteinsagonists

Papers overview

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Highly Cited
2006
Highly Cited
2006
Electrokinetic protein preconcentration using a simple glass/poly(dimethylsiloxane) microfluidic chip.
We discovered that a protein concentration device can be constructed using a simple one-layer fabrication process. Microfluidic… 
Highly Cited
1999
Highly Cited
1999
Interaction of the P-glycoprotein multidrug transporter (MDR1) with high affinity peptide chemosensitizers in isolated membranes, reconstituted systems, and intact cells.
Highly Cited
1997
Highly Cited
1997
Inhibition of drug transport by genistein in multidrug-resistant cells expressing P-glycoprotein.
Highly Cited
1996
Highly Cited
1996
The Cytotoxicity of Tumor Necrosis Factor Depends on Induction of the Mitochondrial Permeability Transition*
Complete prevention of the killing of L929 fibroblasts by tumor necrosis factor α (TNF) in the presence of 0.5 μg/ml actinomycin… 
Highly Cited
1994
Highly Cited
1994
Unidirectional fluxes of rhodamine 123 in multidrug-resistant cells: evidence against direct drug extrusion from the plasma membrane.
P-glycoprotein (Pgp), a plasma membrane protein overexpressed in multidrug-resistant tumor cells, is an ATPase thought to… 
Highly Cited
1993
Highly Cited
1993
Interrelationships among fluorometric analyses of spermatozoal function, classical semen quality parameters and the fertility of frozen-thawed bovine spermatozoa.
Highly Cited
1991
Highly Cited
1991
Multidrug resistance activity in human lymphocytes.
Highly Cited
1990
Highly Cited
1990
Toxic injury from mercuric chloride in rat hepatocytes.
Highly Cited
1987
Highly Cited
1987
Separation and functional analysis of bone marrow cells separated by rhodamine-123 fluorescence.
Mouse bone marrow (BM) cells were separated on the basis of fluorescence intensity after labeling with the supravital… 
Highly Cited
1984
Highly Cited
1984
Cross-resistance to rhodamine 123 in Adriamycin- and daunorubicin-resistant Friend leukemia cell variants.
Cross-resistance to rhodamine 123 (Rho-123) has been found in Adriamycin (ADM)-resistant and daunorubicin (DNR)-resistant Friend… 
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