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Rho-Related GTP-Binding Protein RhoJ, human

Known as: Ras-Like Protein Family Member 7B, Tc10-Like GTP-Binding Protein, Ras Homolog Gene Family, Member J 
Rho-related GTP-binding protein RhoJ (214 aa, ~24 kDa) is encoded by the human RHOJ gene. This protein plays a role in the regulation of both GTP… 
National Institutes of Health

Related topics

Related topics

10 relations
Cytoplasmic matrixCytoskeletal ModelingGTP BindingGTP Binding Domain

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
RhoJ Regulates α5β1 Integrin Trafficking to Control Fibronectin Remodeling during Angiogenesis
2020
2020
RhoJ integrates attractive and repulsive cues in directional migration of endothelial cells
During angiogenesis, VEGF acts as an attractive cue for endothelial cells (ECs), while Sema3E mediates repulsive cues. Here, we… 
2020
2020
A Protective Role for RHOJ in NonSmall Cell Lung Cancer Based on Integrated Bioinformatics Analysis
RHOJ is a small G protein characterized by its abundant expression in endothelial cells. Existing research has documented a link… 
2018
2018
RhoJ promotes hypoxia induced endothelial‐to‐mesenchymal transition by activating WDR5 expression
Endothelial‐to‐mesenchymal transition (EndMT) contributes to the pathogenesis of a host of human diseases. RhoJ, a small G… 
2017
2017
Dysregulation of endothelial colony-forming cell function by a negative feedback loop of circulating miR-146a and -146b in cardiovascular disease patients
Functional impairment of endothelial colony-forming cells (ECFCs), a specific cell lineage of endothelial progenitor cells (EPCs… 
2017
2017
The RhoJ-BAD signaling network: An Achilles’ heel for BRAF mutant melanomas
Genes and pathways that allow cells to cope with oncogene-induced stress represent selective cancer therapeutic targets that… 
Review
2016
Review
2016
The Role of RhoJ in Endothelial Cell Biology and Tumor Pathology
Background. RhoJ, an endothelially expressed member of Cdc42 (cell division cycle 42) subfamily of Rho GTPase, plays an important… 
2013
2013
RhoJ modulates melanoma invasion by altering actin cytoskeletal dynamics
Rho family GTPases regulate diverse processes in human melanoma ranging from tumor formation to metastasis and chemoresistance… 
Highly Cited
2011
Highly Cited
2011
Sema3E-PlexinD1 signaling selectively suppresses disoriented angiogenesis in ischemic retinopathy in mice.
During development, the retinal vasculature grows toward hypoxic areas in an organized fashion. By contrast, in ischemic… 
Review
2011
Review
2011
The role of RhoJ in endothelial cell biology and angiogenesis.
RhoJ is an endothelially expressed member of the Cdc42 (cell division cycle 42) subfamily of small Rho GTPases. It is expressed… 
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