Retinoid X Receptors

Known as: Retinoid X Receptor, Receptors, Retinoid X, Receptor, Retinoid X 
Human nuclear Retinoid X Receptors RXRA, RXRB, and RXRG (NR2/RXR Family) are transcriptional regulators composed of N-terminal modulating domain, DNA… (More)
National Institutes of Health

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Biologic DevelopmentCell Differentiation processCell NucleusCell Proliferation
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Highly Cited
2004
Highly Cited
2004
Immunolocalization of peroxisome proliferator-activated receptors and retinoid x receptors in the adult rat CNS
Peroxisome proliferator-activated and retinoid X receptors (PPARs and RXRs) are transcription factors belonging to the steroid… (More)
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Review
2004
Review
2004
Nuclear retinoid receptors and the transcription of retinoid-target genes.
The pleiotropic effects of retinoids are mediated by nuclear retinoid receptors (RARs and RXRs) which are ligand-activated… (More)
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Highly Cited
2000
Highly Cited
2000
Sterol-dependent transactivation of the ABC1 promoter by the liver X receptor/retinoid X receptor.
Tangier disease, a condition characterized by low levels of high density lipoprotein and cholesterol accumulation in macrophages… (More)
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Highly Cited
2000
Highly Cited
2000
Docosahexaenoic acid, a ligand for the retinoid X receptor in mouse brain.
The retinoid X receptor (RXR) is a nuclear receptor that functions as a ligand-activated transcription factor. Little is known… (More)
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Highly Cited
1997
Highly Cited
1997
Terminal differentiation of human liposarcoma cells induced by ligands for peroxisome proliferator-activated receptor gamma and the retinoid X receptor.
Induction of terminal differentiation represents a promising therapeutic approach to certain human malignancies. The peroxisome… (More)
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Highly Cited
1995
Highly Cited
1995
LXR, a nuclear receptor that defines a distinct retinoid response pathway.
We have identified a new retinoid response pathway through which 9-cis retinoic acid (9cRA) activates transcription in the… (More)
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Highly Cited
1993
Highly Cited
1993
Retinoic acid receptors and retinoid X receptors: interactions with endogenous retinoic acids.
The binding of endogenous retinoids and stereoisomers of retinoic acid (RA) to the retinoid nuclear receptors, RA receptor (RARs… (More)
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Highly Cited
1993
Highly Cited
1993
Fatty acids and retinoids control lipid metabolism through activation of peroxisome proliferator-activated receptor-retinoid X receptor heterodimers.
The nuclear hormone receptors called PPARs (peroxisome proliferator-activated receptors alpha, beta, and gamma) regulate the… (More)
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Highly Cited
1992
Highly Cited
1992
9-cis retinoic acid is a high affinity ligand for the retinoid X receptor
All-trans retinoic acid (RA) has previously been shown to modulate the transcriptional properties of the retinoic acid receptor… (More)
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Highly Cited
1992
Highly Cited
1992
Retinoid X receptor interacts with nuclear receptors in retinoic acid, thyroid hormone and vitamin D3 signalling
CELLULAR responsiveness to retinoic acid and its metabolites is conferred through two structurally and pharmacologically… (More)
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