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Retinoid X Receptors

Known as: Retinoid X Receptor, Receptors, Retinoid X, Receptor, Retinoid X 
Human nuclear Retinoid X Receptors RXRA, RXRB, and RXRG (NR2/RXR Family) are transcriptional regulators composed of N-terminal modulating domain, DNA… 
National Institutes of Health

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31 relations
Biologic DevelopmentCell Differentiation processCell NucleusCell Proliferation

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2004
Highly Cited
2004
Retinoic acid receptor α and retinoid X receptor specific agonists reduce renal injury in established chronic glomerulonephritis of the rat
Retinoids, derivatives of vitamin A, inhibit mesangial cell proliferation, glomerular inflammation, and extracellular matrix… 
Highly Cited
2000
Highly Cited
2000
Retinoid receptors: pathways of proliferation inhibition and apoptosis induction in breast cancer cell lines.
In this study we investigated the effects of several selective agonist retinoids (specific for RAR alpha, RAR beta, RAR gamma… 
Highly Cited
1998
Highly Cited
1998
Induction of apoptosis in MCF-7 breast carcinoma cell line by RAR and RXR selective retinoids.
Induction of apoptosis in MCF-7 breast carcinoma cell line by various retinoids was measured by cytofluorimetry and DNA… 
Highly Cited
1996
Highly Cited
1996
RAR and RXR selective ligands cooperatively induce apoptosis and neuronal differentiation in P19 embryonal carcinoma cells
Retinoids cause differentiation in embryonal carcinoma (EC) cells, thus mimicking events in mammalian development. Here, we show… 
Highly Cited
1996
Highly Cited
1996
Activation of retinoid receptors RARα and RXRα induces differentiation and apoptosis, respectively, in HL-60 cells
Induction of granulocytic differentiation in HL-60 myeloid leukemia cells by retinoids is followed by their death via apoptosis… 
Highly Cited
1995
Highly Cited
1995
Calreticulin inhibits vitamin D3 signal transduction.
Calreticulin is a calcium binding protein present primarily in the lumen of the endoplasmic reticulum. However, it can also… 
Highly Cited
1995
Highly Cited
1995
A role for Hsp90 in retinoid receptor signal transduction.
The ubiquitous heat shock protein Hsp90 appears to participate directly in the function of a broad range of cellular signal… 
Highly Cited
1994
Highly Cited
1994
BmCF1, a Bombyx mori RXR-type receptor related to the Drosophila ultraspiracle.
A PCR approach has been used to obtain an ovarian cDNA clone from the silkmoth Bombyx mori, encoding a 50 kDa protein (BmCF1… 
Highly Cited
1993
Highly Cited
1993
Effects of novel retinoic acid compound, 9-cis-retinoic acid, on proliferation, differentiation, and expression of retinoic acid receptor-alpha and retinoid X receptor-alpha RNA by HL-60 cells.
Retinoic acid modulates proliferation and differentiation of a wide variety of normal and leukemic cells through two distinct… 
Highly Cited
1982
Highly Cited
1982
Enhanced inhibition of mammary carcinogenesis by combined treatment with N-(4-hydroxyphenyl)retinamide and ovariectomy.
Bilateral ovariectomy and dietary administration of the retinoid N-(4-hydroxyphenyl)retinamide (4-HPR) are both effective… 
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