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A cDNA for a rat vesicular monoamine transporter, designated MAT, was isolated by expression cloning in a mammalian cell line (CV… Expand Amphetamine and cocaine are stimulant drugs that act on central monoaminergic neurons to produce both acute psychomotor… Expand The discovery of neuroleptic drugs in 1952 provided a new strategy for seeking a biological basis of schizophrenia. This entailed… Expand Micropuncture and morphologic studies were performed in six groups of male Munich-Wistar rats after removal of the right kidney… Expand Abstract The Marfan syndrome is a dominantly inherited disorder of connective tissue with multisystem involvement. The cardiac… Expand A process for the treatment of sewage wherein the sludge is innoculated with a bacteria, L. plantarum, and a carbohydrate such as… Expand After the administration of reserpine, the in vitro tyrosine hydroxylase activity increases in rat, guinea-pig, mouse and rabbit… Expand The "catecholamine hypothesis of affective disorders" proposes that some, if not all, depressions are associated with an absolute… Expand Introduction LITTLE IS known about the possible etiological biochemical factors relating to depressive reactions. Clinical… Expand THE depletion by reserpine of storage in the body of 5-hydroxytryptamine (‘Serotonin’) and of the catechol amines is now well… Expand