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Recombinant Stem Cell Factor

Known as: c-Kit Ligand, Steel Factor, Recombinant Human Stem Cell Factor 
A therapeutic glycoprotein cytokine chemically identical to or similar to endogenous human stem cell factor with hematopoietic activity. Recombinant… Expand
National Institutes of Health

Papers overview

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Review
2011
Review
2011
Emerging data suggests that host immune cells with a suppressive phenotype represent a significant hurdle to successful therapy… Expand
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Highly Cited
1999
Highly Cited
1999
Mast cells (MCs) arise in situ from circulating stem cell factor (SCF)-dependent committed progenitors (PrMCs) and accumulate at… Expand
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1997
1997
The effect of recombinant human IL-4 (rhIL-4) on the development of recombinant human stem cell factor-dependent fetal liver… Expand
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Highly Cited
1994
Highly Cited
1994
Steel (SI) and white spotting (W) loci encode steel factor (c-kit ligand) and the c-kit tyrosine kinase receptor, respectively… Expand
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Highly Cited
1993
Highly Cited
1993
The c-kit proto-oncogene encodes a receptor tyrosine kinase. Binding of c-kit ligand, stem cell factor (SCF) to c-kit receptor (c… Expand
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Highly Cited
1992
Highly Cited
1992
We have previously shown the development in vitro of tryptase+ human mast cells from fetal liver cells cocultured with murine 3T3… Expand
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Highly Cited
1991
Highly Cited
1991
DESPITE the importance of germ cells to the survival of species, surprisingly little is known about their embryological origin… Expand
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Highly Cited
1991
Highly Cited
1991
Recombinant human stem cell factor (SCF) is homologous with recombinant rat SCF (rrSCF) and is a ligand for c-kit. We determined… Expand
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Highly Cited
1991
Highly Cited
1991
Mast cell development is a complex process that results in the appearance of phenotypically distinct populations of mast cells in… Expand
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Highly Cited
1991
Highly Cited
1991
Stem cell factor (SCF) is the ligand for the receptor encoded by the c-kit proto-oncogene. Mutations of either c-kit or the SCF… Expand
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