FAQ

Recombinant Stem Cell Factor

Known as: c-Kit Ligand, Steel Factor, Recombinant Human Stem Cell Factor 
A therapeutic glycoprotein cytokine chemically identical to or similar to endogenous human stem cell factor with hematopoietic activity. Recombinant… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1991-2017
024619912017

Related topics

Related topics

12 relations
Cytokine Receptor ActivationHematopoietic stem cellsIL3 geneInterleukin-3
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ancestim

Related mentions per year

Related mentions per year

1958-2018
1960198020002020
Recombinant Stem Cell Factor
Hematopoietic stem cells
Interleukin-3
Stem Cell Factor
IL3 gene
immunopotentiation

Papers overview

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2005
2005
Stem cell factor improves SCID-repopulating activity of human umbilical cord blood-derived hematopoietic stem/progenitor cells in xenotransplanted NOD/SCID mouse model
Summary:Poor in vivo homing capacity of hematopoietic stem/progenitor cells (HS/PCs) from umbilical cord blood (UCB) can be… (More)
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2003
2003
C-kit positive porcine bone marrow progenitor cells identified and enriched using recombinant stem cell factor.
Porcine haematological studies have been hampered by the lack of monoclonal antibodies against porcine CD34 or CD117 expressed on… (More)
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Highly Cited
1999
Highly Cited
1999
T Helper Cell Type 2 Cytokine–Mediated Comitogenic Responses and Ccr3 Expression during Differentiation of Human Mast Cells in Vitro
Mast cells (MCs) arise in situ from circulating stem cell factor (SCF)-dependent committed progenitors (PrMCs) and accumulate at… (More)
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1997
1997
The effect of recombinant stem cell factor on human skin and lung mast cells and basophil leukocytes
Recombinant human stem cell factor (rhSCF) induced histamine release from human skin and lung mast cells but had no effect on… (More)
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1994
1994
In vivo synergy between recombinant human stem cell factor and recombinant human granulocyte colony-stimulating factor in baboons enhanced circulation of progenitor cells.
Recombinant human stem cell factor (rhSCF) and recombinant human granulocyte colony-stimulating factor (rhG-CSF) are synergistic… (More)
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1994
1994
Recombinant stem cell factor-induced mast cell activation and smooth muscle contraction in human bronchi.
The effect of human recombinant stem cell factor (SCF) on inflammatory mediator release and smooth muscle contraction was… (More)
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1992
1992
Recombinant human stem cell factor stimulates differentiation of mast cells from dispersed human fetal liver cells.
We have previously shown the development in vitro of tryptase+ human mast cells from fetal liver cells cocultured with murine 3T3… (More)
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1991
1991
The role of recombinant stem cell factor in early B cell development. Synergistic interaction with IL-7.
The cDNA for stem cell factor was recently isolated from Buffalo rat liver cells (BRL-3A) and recombinant rat stem cell factor… (More)
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1991
1991
Human burst-forming units-erythroid need direct interaction with stem cell factor for further development.
To understand the factors that regulate the early growth and development of immature erythroid progenitor cells, the burst… (More)
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1991
1991
The effects on hematopoiesis of recombinant stem cell factor (ligand for c-kit) administered in vivo to mice either alone or in combination with granulocyte colony-stimulating factor.
Stem cell factor (SCF) is the ligand for the receptor encoded by the c-kit proto-oncogene. Mutations of either c-kit or the SCF… (More)
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