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Recombinant Platelet-Derived Growth Factor

Known as: Platlet-Derived Growth Factor, rPDGF 
Expressed in platelets, human Platelet-Derived Growth Factor (PDGF/VEGF Family) is a mitogenic factor for mesenchymal cells characterized by a motif… 
National Institutes of Health

Papers overview

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Highly Cited
1995
Highly Cited
1995
Growth factors in porcine full and partial thickness burn repair. Differing targets and effects of keratinocyte growth factor, platelet-derived growth factor-BB, epidermal growth factor, and neu…
The topical application of recombinant growth factors such as epidermal growth factor, platelet-derived growth factor-BB… 
Highly Cited
1994
Highly Cited
1994
Tissue repair processes in healing chronic pressure ulcers treated with recombinant platelet-derived growth factor BB.
Cellular and molecular mechanisms responsible for the observed vulnerary effects of recombinant human platelet-derived growth… 
Highly Cited
1994
Highly Cited
1994
A phase II study to evaluate recombinant platelet-derived growth factor-BB in the treatment of stage 3 and 4 pressure ulcers.
OBJECTIVE To determine the efficacy of the daily topical application of recombinant platelet-derived growth factor-BB (rPDGF-BB… 
Highly Cited
1993
Highly Cited
1993
Platelet-derived growth factor inhibits bone regeneration induced by osteogenin, a bone morphogenetic protein, in rat craniotomy defects.
Platelet-derived growth factor (PDGF) is a potent moderator of soft tissue repair through induction of the inflammatory phase of… 
Highly Cited
1992
Highly Cited
1992
Platelet-derived growth factor BB for the treatment of chronic pressure ulcers
Highly Cited
1992
Highly Cited
1992
Recombinant Human Platelet-derived Growth Factor-BB for the Treatment of Chronic Pressure Ulcers
A randomized phase I/II double-blind, placebo-controlled study was designed to evaluate 1, 10, and 100 µg/ml (0.01, 0.1, and 1.0… 
1991
1991
Expressions of the low density lipoprotein receptor and 3-hydroxy-3-methylglutaryl coenzyme A reductase genes are stimulated by recombinant platelet-derived growth factor isomers.
The plausible role that platelet-derived growth factor (PDGF) has in the localized pathophysiological changes that occur in the… 
Highly Cited
1990
Highly Cited
1990
Different effects of platelet-derived growth factor isoforms on rat vascular smooth muscle cells.
Highly Cited
1989
Highly Cited
1989
Ca2+-channel blockers inhibit the action of recombinant platelet-derived growth factor in vascular smooth muscle cells.
Human platelet-derived growth factor (PDGF) is mainly composed of two polypeptide chains (PDGF-AB). All three possible dimeric… 
Highly Cited
1988
Highly Cited
1988
In vivo incisional wound healing augmented by platelet-derived growth factor and recombinant c-sis gene homodimeric proteins
Human platelet-derived growth factor (hPDGF) is likely to be important in stimulating tissue repair, based upon its in vivo… 
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