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Recombinant Platelet-Derived Growth Factor

Known as: Platlet-Derived Growth Factor, rPDGF 
Expressed in platelets, human Platelet-Derived Growth Factor (PDGF/VEGF Family) is a mitogenic factor for mesenchymal cells characterized by a motif… Expand
National Institutes of Health

Papers overview

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Highly Cited
2007
Highly Cited
2007
BACKGROUND Nonhealing wounds are a major, functionally-limiting medical problem impairing quality of life for millions of people… Expand
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Highly Cited
1995
Highly Cited
1995
Some human chronic dermal wounds treated with recombinant platelet-derived growth factor-BB (rPDGF-BB) show increased healing… Expand
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1994
1994
Cellular and molecular mechanisms responsible for the observed vulnerary effects of recombinant human platelet-derived growth… Expand
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Highly Cited
1992
Highly Cited
1992
A randomized phase I/II double-blind, placebo-controlled study was designed to evaluate 1, 10, and 100 micrograms/ml (0.01, 0.1… Expand
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Highly Cited
1992
Highly Cited
1992
A randomised, phase I/II, double-blind, placebo-controlled study was designed to assess the effect of topically applied… Expand
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Highly Cited
1992
Highly Cited
1992
Recombinant platelet-derived growth factor (BB homodimer, rPDGF-BB), transforming growth factor beta 1 (rTGF-beta 1), and basic… Expand
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Highly Cited
1990
Highly Cited
1990
To examine the effects of recombinant growth factors in vivo, impaired wound healing was studied in genetically diabetic C57BL… Expand
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1989
1989
Human platelet-derived growth factor (PDGF) is mainly composed of two polypeptide chains (PDGF-AB). All three possible dimeric… Expand
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1989
1989
Stimulation of serum-starved NIH-3T3 cells with 20 ng/ml recombinant platelet-derived growth factor BB (rPDGF) results in the… Expand
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Highly Cited
1988
Highly Cited
1988
Human platelet-derived growth factor (hPDGF) is likely to be important in stimulating tissue repair, based upon its in vivo… Expand
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