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Low density lipoprotein causes general cellular activation with increased phosphatidylinositol turnover and lipoprotein catabolism.
Low density lipoprotein (LDL), at concentrations high enough for receptor binding but not high enough to saturate the receptor, induces activation of phosphatidylinositol (PtdIns) turnover in aExpand
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Comparison of Soluble Sugar Degradation in Soybean Seed under Simulated Tropical Storage Conditions
Storage of soybean [Glycine max (L.) Merr.] seed under tropical conditions can lead to deterioration that affects product taste and color. A study was designed to assess the effect of extreme storageExpand
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The platelet‐derived growth factor isomers, PDGF‐AA, PDGF‐AB and PDGF‐BB, induce contraction of vascular smooth muscle cells by different intracellular mechanisms
The effect of human recombinant platelet‐derived growth factor (PDGF) isoforms, (r)PDGF‐AA, PDGF‐AB and PDGF‐BB, on contractility of rat aortic rings as well as on intercellular free Ca2+ ([Ca2+]i),Expand
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Rapid activation of human platelets by low concentrations of low-density lipoprotein via phosphatidylinositol cycle.
The interaction of low-density lipoprotein (LDL) with the human platelet was investigated with regard to saturable high-affinity binding, shape change, cytosolic free Ca2+ concentration,Expand
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Stereospecific modulation of the calcium channel in human erythrocytes by cholesterol and its oxidized derivatives.
To study the effect of cholesterol and its pathophysiologically important oxidized derivatives (OSC) on the calcium entry channel, the human red blood cell was used as a model system. The calciumExpand
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Novel Cellular Activities for Low Density Lipoprotein in Vascular Smooth Muscle Cells
Hyperlipidemia and hypertension play important roles in the pathogenesis of atherosclerosis. To investigate the underlying intraceiiular mechanisms, we studied the effect of various concentrations ofExpand
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Green tea polyphenols inhibit human vascular smooth muscle cell proliferation stimulated by native low-density lipoprotein.
This study investigated whether human vascular smooth muscle cell proliferation induced by native low-density lipoprotein (LDL) is affected by green tea catechins. Furthermore, the effects of nativeExpand
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Intracellular free calcium concentration and thromboxane A2 formation of vascular smooth muscle cells are influenced by fish oil and n-3 eicosapentaenoic acid.
UNLABELLED The effect of fish oil and n-3 eicosapentaenoic acid (EPA) on intracellular free calcium concentration ([Ca2+]i) and thromboxane B2 (TXB2) formation in resting and stimulated cultured ratExpand
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Attenuation of the low-density-lipoprotein-activated phosphoinositide signalling system by calcium blockers in human lymphocytes.
1. The capacity of low-density lipoprotein-cholesterol (40 micrograms/ml) to stimulate both the phosphoinositide cycle and the dislocation of the phospholipid- and calcium-dependent protein kinase CExpand
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Vasoconstriction: a novel activity for low density lipoprotein.
Low density lipoprotein plays an important role in the pathogenesis of atherosclerosis. Cumulative addition of 1-30 micrograms/ml of LDL from normolipidemic subjects produced a dose-dependentExpand
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