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Recombinant Macrophage Inflammatory Protein-2 Alpha

Known as: CXCL2, MIP2A Protein 
A therapeutic analogue of the endogenous CXC cytokine macrophage inflammatory protein-2 alpha. Macrophage inflammatory protein-2 alpha attracts and… 
National Institutes of Health

Related topics

Related topics

2 relations
CXCL2 gene

Broader (1)

CXCL2 protein, human

Papers overview

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Highly Cited
2018
Highly Cited
2018
CD163 Is Required for Protumoral Activation of Macrophages in Human and Murine Sarcoma.
Recent findings have shown the significance of CD163-positive macrophages in tumor progression, yet there have been few studies… 
Highly Cited
2014
Highly Cited
2014
Interplay of host microbiota, genetic perturbations, and inflammation promotes local development of intestinal neoplasms in mice
The development of serrated polyps in the cecum is driven by the interplay among genetic changes in the host, an inflammatory… 
2013
2013
NTHi induction of Cxcl2 and middle ear mucosal metaplasia in mice
Chronic otitis media (COM) develops after sustained inflammation and is characterized by secretory middle ear epithelial… 
2012
2012
A macrophage subpopulation recruited by CC chemokine ligand-2 clears apoptotic cells in noninfectious lung injury.
CC chemokine ligand-2 (CCL2)/monocyte chemoattractant protein (MCP)-1 expression is upregulated during pulmonary inflammation… 
2011
2011
CXCL2 mediates lipopolysaccharide-induced osteoclastogenesis in RANKL-primed precursors.
Highly Cited
2011
Highly Cited
2011
Lymphocyte function antigen‐1 regulates neutrophil recruitment and tissue damage in acute pancreatitis
Leucocyte infiltration is a rate‐limiting step in the pathophysiology of acute pancreatitis (AP) although the adhesive mechanisms… 
Highly Cited
2010
Highly Cited
2010
A chemotactic gradient sequestered on endothelial heparan sulfate induces directional intraluminal crawling of neutrophils.
During infection, chemokines sequestered on endothelium induce recruitment of circulating leukocytes into the tissue where they… 
Highly Cited
2009
Highly Cited
2009
STAT3 controls the neutrophil migratory response to CXCR2 ligands by direct activation of G-CSF-induced CXCR2 expression and via modulation of CXCR2 signal transduction.
Neutrophil mobilization, the release of neutrophils from the bone marrow reserve into circulating blood, is important to increase… 
Highly Cited
2007
Highly Cited
2007
IL-1beta disrupts postnatal lung morphogenesis in the mouse.
Pulmonary inflammation and increased production of the inflammatory cytokine IL-1beta are associated with the development of… 
Highly Cited
2006
Highly Cited
2006
Lipopolysaccharide induces CXCL2/macrophage inflammatory protein‐2 gene expression in enterocytes via NF‐κB activation: independence from endogenous TNF‐α and platelet‐activating factor
CXCL2 (macrophage inflammatory protein‐2 (MIP‐2)), a critical chemokine for neutrophils, has been shown to be produced in the rat… 
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