Skip to search formSkip to main contentSkip to account menu

Recombinant Interleukin-18

Known as: Interleukin-18, Interferon-Gamma-Inducing Factor, IL-18 
A recombinant therapeutic agent which is chemically identical to or similar to the endogenous cytokine interleukin-18 (IL-18). Produced primarily by… 
National Institutes of Health

Related topics

Related topics

8 relations
CXCL10 geneIL18 geneInhibition of Cell ProliferationNCIt Antineoplastic Agent Terminology

Broader (1)

Interleukin-18

Narrower (1)

SB-485232

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2009
Review
2009
Role of interleukin-18 in the development and pathogenesis of AIDS.
Interleukin-18 is a proinflammatory, proapoptotic, and proatherogenic cytokine belonging to the interleukin-1 family of cytokines… 
Review
2005
Review
2005
Rheumatoid arthritis: non-tumor necrosis factor targets
Purpose of reviewThe treatment of rheumatoid arthritis has been revolutionised in recent years with the advent of biologic… 
2004
2004
Helicobacter pylori Infection Induces Interleukin-18 Production in Gastric Epithelial (AGS) Cells
Helicobacter pylori colonization of the stomach results in a chronic–active gastritis characterized by mucosal infiltration of… 
2003
2003
Inflammatory status in sepsis alters efficacy of interleukin-18 binding protein therapy*
ObjectiveSepsis remains a serious clinical problem, and multiple attempts at blocking inflammation have failed to decrease… 
2003
2003
Inhibition of lipopolysaccharide/ATP-induced release of interleukin-18 by KN-62 and glyburide.
2002
2002
Interleukin‐18 enhances HIV‐1 production in a human chronically‐infected T cell line (H9‐V)
Interleukin‐18 (IL‐18) is a recently identified immunoregulatory cytokine expressed by activated macrophages, that induces… 
2002
2002
High-Dose Recombinant Interleukin-18 Induces an Effective Th1 Immune Response to Murine MOPC-315 Plasmacytoma
Interleukin (IL)-18 has profound antitumor activity when administered at high doses as a single agent for prolonged periods in… 
2001
2001
Interleukin‐18 enhances the production of interleukin‐8 by eosinophils
Interleukin‐18 (IL‐18), a proinflammatory cytokine, leads to IFN‐γ production by NK or T cells, induces Th1 differentiation and… 
2000
2000
A comparative analysis of the antigenic, structural, and functional properties of three different preparations of recombinant human interleukin-18.
We compared the structural and functional properties of three recombinant human interleukin-18 (rIL-18) preparations… 
Highly Cited
1999
Highly Cited
1999
Intracellular production of interleukin-18 in human epithelial-like cell lines is enhanced by hyperosmotic stress in vitro
Abstract Interleukin-18 is a novel multifunctional cytokine, which enhances natural killer cell activity and promotes the… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)