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Recombinant Interleukin-18

Known as: Interleukin-18, Interferon-Gamma-Inducing Factor, IL-18 
A recombinant therapeutic agent which is chemically identical to or similar to the endogenous cytokine interleukin-18 (IL-18). Produced primarily by… Expand
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
Although Francisella tularensis subsp. tularensis is known to cause extensive tissue necrosis, the pathogenesis of tissue injury… Expand
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Highly Cited
2009
Highly Cited
2009
Assessment of allergenic potential of chemicals is performed using animal models, such as the murine local lymph node assay… Expand
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Highly Cited
2008
Highly Cited
2008
Aluminium adjuvants, typically referred to as ‘alum’, are the most commonly used adjuvants in human and animal vaccines worldwide… Expand
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Highly Cited
2008
Highly Cited
2008
Interleukin (IL)-18 production and pulmonary function were evaluated in patients with chronic obstructive pulmonary disease (COPD… Expand
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Review
2007
Review
2007
Interleukin-18 (IL-18) was discovered as an interferon-gamma-inducing factor and had a critical role in inflammatory and immune… Expand
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Highly Cited
2006
Highly Cited
2006
Interleukin-18 (IL-18) is a novel pro-inflammatory cytokine which has been implicated to play a pathogenic role in rheumatoid… Expand
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Highly Cited
2005
Highly Cited
2005
OBJECTIVE Activated innate immunity is thought to be involved in the pathogenesis of metabolic syndrome and type 2 diabetes… Expand
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Highly Cited
2001
Highly Cited
2001
The effects of the pro-inflammatory cytokine interleukin-18 (IL-18) were investigated on both normal and isolated N-methyl-D… Expand
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Highly Cited
2000
Highly Cited
2000
Interleukin-18 (IL-18) is not only a co-stimulus for the induction of interferon-gamma but also has direct proinflammatory… Expand
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Highly Cited
1996
Highly Cited
1996
The novel cytokine interferon-gamma-inducing factor (IGIF) augments natural killer (NK) cell activity in cultures of human… Expand
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